摘要
肺癌是目前全世界发病率最高的恶性肿瘤,其病死率也居于前列.因此,对肺癌的早期诊断及早期治疗对于降低肺癌患者的病死率以及改善患者生存质量至关重要.传统的肺癌诊断方法包括影像学检查以及病理学检查,现在仍然被临床所采用.但鉴于以上检查手段的敏感性、特异性、适用度等方面存在一定局限,近年来有关肺癌早期诊断、治疗及预后的分子标志物的研究愈来愈受到关注.本文就甲状腺转录因子-1的生物作用及其在肺癌诊断、治疗及预后方面的研究进展作一综述.
Lung cancer is the malignant carcinoma with the highest incidence and mortality all over the world. Consequently, early diagnosis and treatment may be very useful in reducing the mortality and improving the survival quality of patients. Traditional diagnostic methods of lung cancer still be used in chinic now, including imaging examinations and pathological examinations. Because of the limitation in sensitivity,specificity,and adaptability, the molecule markers for early diagnosis and treatment of lung cancer have received more and more attentions in recent years. In this article, the mechanism and treatment, and evaluation of prognosis of lung
出处
《国际呼吸杂志》
2013年第18期1412-1417,共6页
International Journal of Respiration
关键词
肺癌
甲状腺转录因子-1
Lung cancer
Thyroid transcription factor 1
