摘要
目的：探讨了卡前列素氨丁三醇治疗产后出血高危因素孕妇的疗效观察。方法：回顾性分析我院2010年2月～2013年2月收治的80例产后出血高危因素剖宫产产妇的临床资料，随机分为对照组和观察组，观察组产妇在常规治疗的基础上给予宫体注射卡前列素氨丁三醇治疗，对照组产妇在常规治疗的基础上给予米索前列醇、垂体后叶素宫体注射治疗。结果：产后2h、4h出血量比较，观察组均显著低于对照组，差异有显著性意义（P〈0.05）；观察组产后出血发生率为12.5%，对照组产后出血发生率为31.91%，两组对比统计学有显著性差异（P〈0.05）；观察组止血时间显著低于对照组，差异有显著性意义（P〈0.05）；观察组输血患者2例（5%），输血患者10例（25%），观察组显著低于对照组，两组差异有显著性意义（P〈0.05）；观察组没有患者行子宫切除术，对照组有2例行子宫切除术，统计学均有显著性差异（P〈0.05）。观察组不良反应3例，对照组2例。结论：预防性宫体注射卡前列素氨丁三醇在产后出血高危因素孕妇剖宫产术中能明显减少产后出血量，降低产后出血发生率和输血率，缩短止血时间，减少近远期并发症，值得临床推广。
Objective：To investigate the carboprost tromethamine in the treatment of postpartum hemorrhage as risk factors in pregnant wonmen.Methods：A retrospective analysis of 80 cases of postpartum hemorrhage risk factors for cesarean section performed clinical data in our hospital from February 2010 to February 2013,were randomly divided into control group and observation group,were observed in the conventional treatment group,the observation group of delivery women on the basis of conventional therapy for uterine body injected by carboprost trometamol, control group delivery women on the basis of routine treatment, given misoprostol, pituitrin injection in the treatment of uterine body.Results：Postpartum 2h, 4h amount of bleeding in the observation group were significantly lower than the control group, the difference was significant （P〈0.05）;observation group postpartum hemorrhage rate was 12.5%in the control group was 31.91%of postpartum hemorrhage, between two groups was statistically significant difference （P〈0.05）;observation group was significantly lower than the control bleeding group, the difference was statistically significant （P〈0.05）;observation group：2 patients transfusion （5%）,blood transfusion in patients 10 cases （25%） in the observation group was significantly lower than the control group, the difference was statistically significant （P〈0.05）;observation group underwent hysterectomy without the control group, two routine hysterectomy, were statistically significant difference （P〈0.05）. Adverse reactions observed in 3 cases,2 cases of the control group. Conclusion：The prevention of intrauterine injection of carboprost trometamol in the risk factors of postpartum hemorrhage in cesarean section surgery can significantly reduce the amount of postpartum hemorrhage, reducing the incidence rate of postpartum hemorrhage and blood transfusion rate, shorten the bleeding time, reduce the complication, is worth the clinical promotion.
出处
《中国医药导刊》
2013年第9期1510-1511,共2页
Chinese Journal of Medicinal Guide
关键词
卡前列素氨丁三醇
产后出血
高危因素
Carboprost tromethamine Postpartum hemorrhage Risk factors
