摘要
本实验分别用Dig标记的IL - 2、IL - 2R、IL - 6cRNA探针在 37例自身免疫性甲状腺疾病患者甲状腺石蜡切片上行原位杂交 ,结果显示患者甲状腺浸润细胞中有IL - 2、IL - 2R、IL - 6mRNA的异常表达 ,其分布与病理损伤部位一致 ,这种异常表达是引起甲状腺内免疫功能紊乱的重要因素之一。
To study immune pathogenesis of autoimmune thyroid disease.Methods To measure IL-2,Il-2R and IL-6 mRNA expression in situ thyroid tissue by IL-2,IL-2R,Il-6mDNA probes,all were labeled by dig.Result IL-2,Il-2R and IL-mRNA were abnormal expression in cytoplasma of infiltrating cell from thyroid sample of AITD.Conclusion Abnormal expression is an importarnt factor causing immune function disorder in thyroid.
出处
《云南医药》
CAS
2000年第5期373-374,共2页
Medicine and Pharmacy of Yunnan
基金
美国中华医学基金会提供资助!(CMB 1995年 )
