摘要
目的探讨胰腺癌多层螺旋CT(MSCT)影像学表现与肿瘤侵犯的关系。方法选择我院2009年12月—2012年2月收治的胰腺癌患者40例,收集其肿瘤组织病理切片和石蜡块进行免疫组织化学染色。所有患者术前进行MSCT三期扫描,观察胰腺周围血管及组织侵犯情况,比较周围血管及组织侵犯组与未侵犯组的肿瘤特征。结果40例患者中胰腺周围血管侵犯25例,未侵犯周围血管15例;胰腺周围组织侵犯19例,未侵犯周围组织21例。侵犯周围血管组与未侵犯周围血管组、侵犯周围组织组与未侵犯周围组织组肿瘤部位、淋巴转移率、肝脏转移率、国际抗癌协会癌症临床分期(UICC分期)、病理分级及血管内皮生长因子(VEGF)、血管内皮生长因子C(VEGF-C)、基质金属蛋白酶-2(MMP-2)、基质金属蛋白酶-9(MMP-9)、CD34阳性率比较,差异均无统计学意义(P>0.05)。结论 MSCT可显示胰腺周围血管侵犯、周围组织侵犯,可帮助诊断胰腺癌,用于观察微小病变,指导手术。
Objective To study the correlation between pancreatic cancer multilayer spiral CT （MSCT） imaging find- ings and tumor invasion. Methods 40 patients with pancreatic tumor admitted to our hospital from December 2009 to February 2012 were involved. Pathological section of tumor tissues and paraffin block were collected to perform immunochemical staining. All the patients were given MSCT muhiphase dynamic scanning to observe vascular invasion and tissue invasion, and the features of tumor were compared between invasion group and non - invasion group. Results Among the 40 patients, 25 cases showed vascu- lar invasion and 15 cases did not, 19 cases showed surrounding tissues invasion while 21 cases did not. There was no statistically significant difference in tumor location, lymph nodes metastasis rate, liver metastasis rate, UICC staging, pathological grading and positive rate of VEGF, VEGF- C, MMP -2, MMP- 9, CD34 between vascular invasion group and non -vascular invasion group （ P 〉 0. 05 ） , so was between surrounding tissues invasion group and non - surrounding tissues invasion group （ P 〉 0. 05 ） ,Conclusion MSCT scan of the pancreatic surrounding tissues invasion and vascular invasion is conducive to the diagnosis of pancreatic tumor. The image can also be used to observe minimal lesion and guide surgery.
出处
《中国全科医学》
CAS
CSCD
北大核心
2013年第24期2852-2854,共3页
Chinese General Practice
关键词
胰腺癌
体层摄影术
螺旋计算机
肿瘤转移
相关性
Pancreatic neoplasms
Tomography, spiral computed
Neoplasm metastasis
Correlation
