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冠心病血管内皮功能的无创评估 被引量:17

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摘要 目的 :通过无创的超声检查来阐明冠心病 (CHD)的血管内皮功能与冠状动脉 (冠脉 )病变的关系。方法 :对 110例确诊或怀疑 CHD而行冠脉介入检查及治疗者采用超声技术来检测其肱动脉的血管内皮依赖性舒张功能与硝酸甘油介导的血管扩张功能。结果 :冠脉狭窄组较冠脉光滑组、不光滑组的流量介导的血管舒张功能受损明显 (P <0 .0 5 )。受损的程度与冠脉病变支数、严重程度 ,吸烟呈正相关 ;与高密度胆固醇量呈负相关。冠脉狭窄组硝酸甘油介导的血管扩张也轻度改变。结论 :CHD患者不仅存在血管形态学狭窄 ,血管内皮功能亦受损 ,并且其受损的程度与冠脉病变严重程度有关。
出处 《临床心血管病杂志》 CAS CSCD 北大核心 2000年第11期491-494,共4页 Journal of Clinical Cardiology
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