摘要
目的 :探讨周围神经端侧吻合后感觉轴突和运动轴突再生的差异以及比较神经端端吻合与端侧吻合的效果。方法 :2 0只雄性 SD大鼠 ,随机分为两组 ,A组为右侧腓神经切断 ,远侧断端与胫神经行端侧吻合 ;B组为右侧腓神经切断 ,即行端端吻合 ;两组大鼠左侧留作正常对照。HRP染色逆行追踪检测轴突再生神经元。结果 :实验侧脊髓前角及脊神经节可见 HRP标记细胞 ,端端吻合效果显著好于端侧吻合 ,端侧吻合后再生纤维中感觉纤维和运动纤维兼而有之。结论
Objective: To compare regeneration of motor fibers with that of sensory fibers by end to side neurorrhaphy and compare the effect of end to side neurorrhaphy with that of end to end neurorrhaphy. Methods: 20 SD rats were randomly divided into two groups: group A and group B. In group A, the right peroneal nerve was sectioned and the distal end was sutured laterally to the tibial nerve; in group B, the right peroneal nerve was sectioned and sutured with end to end neurorrhaphy. All left sides of two groups were used as control. Retrograde transportation of HRP was observed after 28 weeks. Results: The labelled neurons were also found in the anterior horn of the spinal cord and the spinal ganglia. Conclusion: The regenerative nerve fibers had motor fibers as well as sensory fibers by end to side neurorrhaphy. The effect of end to side neurorrhaphy is not as good as that of end to end neurorrhaphy. [
出处
《第二军医大学学报》
CAS
CSCD
北大核心
2000年第12期1184-1185,共2页
Academic Journal of Second Military Medical University
关键词
神经再生
端侧吻合
轴突
周围神经损伤
nerve regeneration
retrograde transportation
HRP
end to side neurorrhaphy
