摘要
目的:观察负压吸引辅助自体血胸腔注射治疗顽固性气胸的临床效果及安全性。方法:选取2010年6月-2012年6月本院收治的顽固性气胸患者124例,将其随机分为对照组和观察组,每组各62例。两组患者均给予胸腔闭式引流管行持续负压吸引,对照组在引流管胸腔内注射5%葡萄糖100 ml加红霉素0.75~1 g;观察组经引流管胸腔内注射自体血5O^100 ml。结果:对照组治疗成功48例,成功率为77.4%(48/62);观察组共治疗成功56例,成功率为90.3%(56/62)。其中对照组术后出现胸痛等不良反应14例,发热3例,观察组则分别为5例、2例。术后3~12个月进行随访调查,对照组病情复发11例,高于观察组的5例,两组比较差异有统计学意义(P<0.05)。结论:负压吸引辅助自体血胸腔注射治疗顽固性气胸具有较好的临床疗效,且预后良好,有利于改善患者的不良症状,降低气胸的复发率,显著提高其生活质量。
Objective：To observe the clinical effect and safety of autologous blood suction assisted thoracic cavity injection in the treatment of intractable pneumothorax.Method：124 patients with intractable pneumothorax from 2010 June to 2012 June in our hospital were selected,and were randomly divided into control group and observation group,each group had 62 cases.Two groups of patients were treated with closed thoracic drainage tube for continuous negative pressure suction,which control group within the drainage tube intrapleural injection of 5% glucose 100 mL plus erythromycin 0.75~1 g;the observation group by thoracic drainage and injection of autologous blood 50~100 mL.Result：In the control group were treated successfully in 48 cases,the success rate was 77.4%（48/62）;the observation group were treated successfully in 56 cases,the success rate was 90.3%（56/62）.The control group was 14 cases of adverse reactions such as chest pain,3 cases of fever,observation group were 5 cases,2 cases.Were followed up 3-12 months after operation,the control group of 11 cases of relapse was higher than that the observation group of 5 cases.There was significant difference between the two groups（P〈0.05）.Conclusion：Negative pressure suction assisted autologous blood pleural injection has a better clinical curative effect to cure intractable pneumothorax,and the prognosis is good,have adverse symptoms improved in patients with pneumothorax,reduce the recurrence rate,improve their quality of life.
出处
《中国医学创新》
CAS
2013年第26期54-55,共2页
Medical Innovation of China
