摘要
目的探讨阿托品联合解磷定微量泵持续静脉泵入在抢救有机磷中毒中的价值。方法回顾性分析47例急性有机磷中毒病例,在常规治疗的基础上,将47例急性有机磷农药中毒患者分为两组:治疗组24例,对照组23例,治疗组采用阿托品与碘解磷定先静脉注射后持续微量泵静脉维持给药方法,对照组采用常规间断分次按时静给药方法。观察比较2组患者的阿托品化时间、阿托品化剂量、阿托品总量、死亡率等。结果治疗组病死率、反跳发生率较对照组显著降低(P<0.05)。而两组阿托品化时间、阿托品总量及疗程均差异无统计学意义(P>0.05)。结论微量泵输注阿托品和解磷定抢救有机磷中毒操作简便,阿托品和解磷定用量易于掌握和调控,抢救成功率高。
Objective To investigate the value of atropine joint phosphate-solubilizing injection by micro pump in acute organophosphorus pesticide poisoning. Methods 47 cases of acute organophosphate poisoning cases were retrospectively analyzed. On the basis of conventional treatment, 47 patients of acute organophosphorus pesticide poisoning were divided into 2 groups： 24 cases of treatment group, 23 cases of control group. The treatment group was given continuous micro pumping treatment besides the atropine and pyraloxime lodide intravenous transfusion treatment. The control group was given the traditional treatment. Compare the time of atropinization, the dosage of atropinization, the total dosage of atropine, the death rate and etc. Results The mortality and rebound rate had decreased significantly in the treatment group （P 〈 0.05）. The time of atropinization, the total dosage of atropine of two groups had no significant difference （P 〉 0.05）. Conclusion The combination of continuous micro pump intravenous transfusion treatment is simple, reliable, the dosage of atropine and pyraloxime lodide is easy to control, and rescue success rate is high.
出处
《中国医药科学》
2013年第18期197-198,210,共3页
China Medicine And Pharmacy
关键词
阿托品
急性有机磷中毒
微量泵
Atropine
Acute organophosphate poisoning
Micro pump
