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宫腔镜术后应用雌激素预防宫腔粘连的效果观察 被引量:14

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摘要 目的评价子宫腔粘连(IUA)患者行官腔镜下宫腔粘连分离术(TCRA)后应用雌激素防止宫腔再粘连的疗效。方法收集210例宫腔粘连患者,按数字表法随机分为观察组110例、对照组100例,均行TCRA治疗,观察组术后采用戊酸雌二醇联合宫内放置宫内节育器(IUD)方案,对照组术后仅行IUD。术后定期随诊,观察月经恢复、妊娠情况,行宫腔镜、阴道超声及肝功检查评价疗效。结果两组手术均获得成功,观察组总有效率为91.8%,对照组总效率为75.0%,观察组疗效优于对照组,两组差异有统计学意义(x^2=10.919,P〈0.05)。术后官腔形态检查两组总治疗有效率82.4%(173/210),观察组总有效率90.9%(100/110),对照组总有效率73.0%(73/100)。术后月经恢复观察组总有效率83.6%(92/110),对照组总有效率72.0%(72/100)。术后观察组正常妊娠率73.5%(61/83),对照组正常妊娠率63.2%(48/76)。结论宫腔镜下TCRA后服用戊酸雌二醇同时宫腔放置IUD对于预防再粘连具有显著的疗效,对于患者术后症状改善、月经恢复、妊娠均有满意的疗效。
作者 陈艳菠
出处 《中国基层医药》 CAS 2013年第22期3448-3449,共2页 Chinese Journal of Primary Medicine and Pharmacy
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