摘要
目的 :检测某些中草药对口腔微生物的抑制杀灭作用。方法 :制备七种中草药水浸液提取物 ,将水浸液提取物分别加至培养基中 ,观察各种口腔微生物的生长速度 ,确定水浸液提取物的最小抑菌量。结果 :夏枯草、金银花、厚朴、菊花、威灵仙、秦艽的水浸液提取物对所试验的口腔微生物生长无明显抑制作用 ,而黄连的水浸液提取物有明显的抑制作用 ,尤其对牙周致病菌牙龈卟啉菌 (初始抑菌量 0 .2 5 0mg ml)、伴放线放线杆菌 (初始抑菌量 0 .12 5mg ml)的抑制作用更强。结论 :黄连可用于某些口腔疾病尤其是牙周疾病的治疗及预防。
Objective: To prove some medicinal herbs' effectiveness on inhibiting the growth of oral microbes. Methods: The experiment was carried out by making herbal aqueous extracts from seven kinds of Chinese medicinal herbs, then adding each herbal extract to the cultures respectively to observe the growth of each tested oral microbe strain and to determine the herbal inhibition to oral microbes quantitatively. Results: The aqueous extract of Chinese goldthread is markedly inhibitory to all of the microbes tested, especially periodontal pathogens such as Actinobacillus actinomycetemcomitans (IIC 0.125 mg/ml) and Porphyromonas gingivalis (IIC 0.250 mg/ml). However, the aqueous extracts of selfheal, honeysuckle, official magnolia, chrysanthemum, Chinese clematis and large-leafed gentian cannot inhibit the growth of oral microbes tested. Conclusion: It can be expected that Chinese goldthread is an ideal choice in dental prevention and treatment, especially for periodontal diseases. [
出处
《口腔医学纵横》
CSCD
2000年第4期279-281,共3页
Journal of Comprehensive Stomatology
基金
TheresearchprojectissponsoredbyResearchFoundationofShandongMedicalUniversity (Number 42 3839)
