摘要
目的探讨可溶性细胞间粘附分子 1(solubleintercellularadhesionmolecule 1,sICAM 1)在急、慢性肝炎的水平及临床意义。方法应用酶联免疫吸附实验检测 6 7例急、慢性肝炎患者血清sICAM 1水平 ,并同时检测肝功能。结果急、慢性肝炎患者血清sICAM 1水平明显高于正常人水平 (P <0 .0 1,P <0 .0 5 ) ,且随着肝细胞损伤程度的加重而升高。结论血清sICAM 1水平可反映肝炎患者的肝细胞坏死程度。
ObjectiveTo observe changes of soluble intercellular adhesion molecule 1(sICAM 1) in patients with acute and chronic viral hepatitis and its clinical significance. MethodsSerum sICAM 1 levels were detected by ELISA in 67 patients with acute and chronic viral hepatitis,and their liver functions were detected at the same time. ResultsSerum sICAM 1 levels in the subjects with acute and chronic viral hepatitis were significantly higher than those in normal controls(P< 0.01 ,P< 0.05 ),and the serum sICAM 1 level increased with the severity of liver damage. ConclusionSerum sICAM 1 level reflects liver damage in hapatitis.
出处
《河北医科大学学报》
CAS
2000年第6期334-336,共3页
Journal of Hebei Medical University
关键词
病毒性肝炎
血清
SICAM-1
ELISA
肝功能试验
hepatitis
viral/diagnosis
intercellular adhesion molecule 1/blood
enzyme linked immunosorbent assay
liver function tests
