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速度向量成像技术评价脑梗死患者颈动脉斑块生物力学特性的初步研究 被引量:8

Preliminary Study of Carotid Atherosclerotic Plaque Biomechanics in Cerebral Infarction Patients by Velocity Vector Imaging
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摘要 目的探讨速度向量成像技术评价颈动脉斑块力学状态的临床应用价值。方法采集脑梗死患者188个颈动脉斑块,非脑梗死患者154个颈动脉斑块,应用速度向量成像技术测量斑块不同部位短轴方向最大应变(Smax)及最大应变率(SRmax)。结果两组斑块肩部SRmax均高于顶部及基底部,顶部SRmax高于基底部;斑块肩部Smax高于顶部及基底部;软斑块肩部SRmax均高于硬斑块肩部,差异有统计学意义(P<0.05)。脑梗死组硬斑块肩部及软斑块肩部SRmax均高于非脑梗死组,差异有统计学意义(P<0.05)。结论速度向量成像技术可定量检测脑梗死患者颈动脉不同性质斑块的力学特性,为临床分析斑块的稳定性提供新的方法。 Aim To evaluate the changes of the strain and the strain rate at carotid atherosclerotic plaque in cer- ebral infarction patients by velocity vector imaging (VVI). Methods 188 carotid plaques in cerebral infarction pa- tients and 154 carotid plaques in patients with no-cerebral infarction were selected. Every plaque was examined by Sie- mens Sequoia 512 with VVI work station. The maximum strain (Smax) and maximum strain rate (SRmax) at the shoul- der, surface and base of plaque in short axis were measured. Results The Smax, SRmax at plaque shoulder were higher significantly than that at plaque surface and plaque base, and the SRmax at plaque surface was higher than that at plaque base in both groups. The SRmax at the soft plaque shoulder was higher than that at the hard plaque in both groups ( P 〈 0. 05 ). The SRmax at plaque shoulder and the soft plaque shoulder in the cerebral infarction group were higher than that in the no-cerebral infarction group ( P 〈 0.05 ). Conclusion VVI technology can be mechanical characteristics of quantitative detection of carotid artery in cerebral infarction patients with different plaques, which provides a new method for clinical analysis of the stability of plaque.
出处 《中国动脉硬化杂志》 CAS CSCD 北大核心 2013年第8期751-754,共4页 Chinese Journal of Arteriosclerosis
关键词 速度向量成像 脑梗死 颈动脉 粥样斑块 Velocity Vector Imagine Cerebral Infarction Carotid Atherosclerotic Plaque
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