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妊娠期糖尿病孕期不同治疗方法与妊娠结局的关系 被引量:15

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摘要 目的:探讨妊娠期糖尿病(GDM)患者孕期不同治疗方法与母儿妊娠结局的关系。方法:对GDM 140例分为3组,A组:胰岛素治疗组+饮食控制31例;B组:饮食控制血糖不满意时用胰岛素治疗35例;C组:单纯饮食控制血糖74例,比较3组母儿妊娠结局。根据孕期首次使用胰岛素孕周将病例分为两组:Ⅰ组32例(平均胰岛素起始孕周26周),Ⅱ组34例(平均胰岛素起始孕周33+3周),比较两组母儿结局。结果:3组血糖基本控制在正常范围,A组剖宫产、妊娠期高血压疾病、酮症、巨大儿、胎儿窘迫、新生儿高胆红素血症、新生儿低血糖发生率低于B组及C组,差异有统计学意义(P<0.05)。早产差异无统计学意义(P>0.05)。Ⅰ组剖宫产率、新生儿高胆红素血症、胎儿窘迫与Ⅱ组差异无统计学意义(P>0.05),而酮症、巨大儿、羊水过多、妊娠期高血压、新生儿低血糖都要低于Ⅱ组差异有统计学意义(P<0.05)。结论:对GDM患者饮食控制同时加用胰岛素治疗,与饮食控制不满意后再加用胰岛素治疗相比,前者可以明显改善母婴结局,尤其是体重指数偏高患者。孕期饮食控制基础上早用胰岛素比晚用胰岛素可以改善母婴结局。
作者 李丽 宋建华
出处 《中国妇幼保健》 CAS 北大核心 2013年第27期4561-4563,共3页 Maternal and Child Health Care of China
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