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尿微量白蛋白检测在早期糖尿病肾病诊断中的应用价值 被引量:28

The application value of urinary microalbumin detection in the early diagnosis of diabetic nephropathy
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摘要 目的探讨尿微量白蛋白检测在早期糖尿病肾病诊断中的应用价值,为临床的诊断和治疗提供有价值的参考依据。方法随机选取我院内分泌科收治的70例2型糖尿病的患者为观察组,选取同期在我院体检的健康受试者为对照组。对比两组受试者的尿微量白蛋白的检测结果,并对不同病程的糖尿病患者尿微量白蛋白的检测阳性率进行对比。结果观察组患者尿微量白蛋白定量检查结果为(60.62±17.91)mg/L,明显高于对照组的(13.47±4.93)mg/L;观察组检测的阳性率为55.71%,明显高于对照组的0.00%;随着糖尿病病程的延长,尿微量白蛋白检测结果的阳性率明显升高。不同糖尿病病程的患者,其尿微量白蛋白检测阳性率比较,其差异均有统计学意义(P<0.05)。结论尿微量白蛋白检测对早期糖尿病肾病有重要的诊断价值,同时在指导临床的治疗、帮助临床对病情的评估以及改善患者的预后均有重要的意义。 Objective To investigate the effect of urinary microalbumin detection in the early diagnosis of diabetic nephropathy,and to provide valuable reference for the clinical diagnosis and treatment of this disease.Methods 70 patients with type 2 diabetes were selected as the observation group in our hospital,while the healthy subjects were selected as the control group.The detection results of urinary albumin were compared between the two groups,and the positive rates of diabetic patients with microalbuminuria in different course of disease were compared.Results The urine albumin concentration was(60.62±17.91)mg/L in the observation group,it significantly higher than that in control group(13.47±4.93) mg/L;the positive rate in observation group was 55.71%,significantly higher than that in control group 0%;with the prolonged duration of diabetes,the positive rate of the detection results of trace albuminuria was significantly elevated;the differences were statistically significant(P0.05).Conclusion The detection of microalbuminuria is valuable for the diagnosis of early diabetic nephropathy.
作者 李东千
出处 《四川医学》 CAS 2013年第7期1083-1084,共2页 Sichuan Medical Journal
关键词 尿微量白蛋白 早期糖尿病肾病 诊断价值 urinary albumin early diabetic nephropathy diagnostic value
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