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阿托伐他汀治疗急性心肌梗死疗效及对血脂水平的影响分析 被引量:12

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摘要 目的研究运用阿托伐他汀于急性心肌梗死患者后的治疗效果及其对调节血脂水平的功能。方法将我院收治的120名心肌梗死患者随机分为两为治疗组(60例)和对照组(60例)。两组均首先按照严格的AMI常规治疗,治疗组在此基础上加用阿托伐他汀10mg/d,对照组则无需给予其他治疗,1个疗程为2个月。同时记录相关并发症情况并在治疗前后空腹检测血脂水平。结果观察治疗1个疗程后,治疗组死亡2例,对照组9例,心律失常、心源性休克、心力衰竭等并发症发生率也较低;治疗组血脂水平被调节得较好,各项指标结果差异有统计学意义(P<0.05)。结论治疗AMI时加用阿托伐他汀可提高治疗效率和降低死亡率,且有效改善血脂水平,此方案值得临床推广。
出处 《四川医学》 CAS 2013年第7期1059-1061,共3页 Sichuan Medical Journal
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  • 1赵成军,贾如意,高成志,马圣庭,虞华鹏,王涛.外周血管病变与非心肌梗死患者冠状动脉病变的临床研究[J].中国全科医学,2007,10(7):544-546. 被引量:2
  • 2BRAUNWALD E, ANTMAN E M, BEASLEY J W,et al. ACC/AHA guidelines for the management of patients with unstable angina and non-ST-segment elevation myocardial infarction: a report of American college of cardiology/American heart association task force of practice guidelines [J].J Am Coll Cardiol, 2000, 36: 970--1062.
  • 3KRISTINA S, JULIA P O, FRUCHART J C, et al. 3-Hydroxy-3-methylglutaryl CoA reducetase inhibi- tors reduce-rllm trlgtyceride levels through modulation of apollpoprote in C-III and lipoprotein lipase[J]. FEBS Lett, 1999, 452:160--164.
  • 4VAN WISSEN S, TRIP M D, SMIHLE T J, et al. Differential hs-CRP reduction in patients with familial hypercholesterolemia treated with aggressive or conventional statin therapy[J]. Atherosclerosis, 2002, 165:361--366.
  • 5DE LEMOS J A, BLAZING M A, WIVIOT S D, et al. Early intensive VS a delayed conservative simvastatin strategy in patients with acute coronary syndromes[J]. JAMA, 2004, 292:1307--1316.
  • 6SCHWARTZ G G, OLSSON A G, EZEKOWITZ M D. et al. Effects of atorvastatin on eady recurrent ischemic events in acute coronary syndrome[J]. JAMA, 2001, 285:1711--1718.
  • 7JONES P, KAFONEK S, LAURORA I, et al. Com- porative dose efficacy study of atorvastatin versus sim- vastatin, pravastatin, lovastatin and fluvastatin in patients with hypercholesterolemia (the carves study)[J]. Am J Cardiol, 1998, 81:582--582.
  • 8KARALIS D G, ROSS A M, VACARI R M, et al. Comparison of eficacy and safety of atorvastatin and simvastatin in patients with dyslipidemia with and without coronary heart disease[J]. Am J Cardiol, 2002, 89:667-671.
  • 9ANDREWS T C, BALLANTYNE C M, HSIA J A, et al. Achieving and maintaining national cholesterol education program low-density lipoprotein cholesterol goals with five statins[J]. Am J Med, 2001, 11 : 185 --189.
  • 10Expert panel on detection, evaluation and treatment of high blood cholesterol in adults. Third report of the national cholesterol education program (NCEP)expert panel on detection, evaluation and treatment of high blood cholesterol in adults final report[J].Circulation, 2002,106 : 3143- 3421.

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