摘要
目的探讨慢性心衰患者NT-proBNP、cTnT、hs-CRP的检测和意义。方法测定慢性心衰患者(43例)和健康者(21例)NT-proBNP、cTnT和hs-CRP水平,并进行统计学分析。结果慢性心衰患者cTnT、hs-CRP、NT-proBNP血浆检测水平(中位值)分别为:2790.0ng/mL、0.041ng/mL、7.330mg/L。健康者分别为54.16ng/mL、0.003ng/mL、1.050mg/L。慢性心衰患者cTnT、hs-CRP、NT-proBNP水平均明显高于健康者(P<0.05)。慢性心衰患者NT-proBNP水平与cTnT水平、hs-CRP水平呈正相关(r=0.612,P<0.05;r=0.293,P<0.05)。心衰患者治疗后NT-proBNP、cTnT的水平低于治疗前(P<0.05);但治疗前后的hs-CRP水平差异没有统计学意义(P>0.05)。结论 NT-proBNP、cTnT、hs-CRP的联合检测有助于慢性心衰患者的诊断与疗效观察。
Objeetive To study the clincal significance of plasma levels of NT-proBNP. cTnT,hs-CRP in patients with chronic heart failure（CHF） and the possible pathophysiologie implications. Methods The plasma levels of NT-proBNP.cTnT.hs-CRP of 44 patients with CHF （CHF group） and 21 healthy people（control group） were tested. Results The levels of NT-proBNP,cTnT, hs-CRP（median value） in CHF group were 2 790.0 ng/mL, 0. 041 ng/mL, 7. 330 mg/L, respectively, and those of control group were 54.16 ng/mL.0. 003 ng/mL.1. 050 mg/L,respectively. CHF group and control group were statistically different in NT-proB- NP, eTnT, hs-CRP levels（P〈0.05）. NT-proBNP were postively correlative with cTnT and hs-CRP level in CHF group（r= 0.612, 0. 293,P〈0.05）. The levels of NT-proBNP and eTnT in patients with heart failure after treatment was significantly lower than that before treatment（P〈0.05）, except for hs-CRP（P〉0.05）. Conclusion The combined detection of NT-proBNP, cTnT,and Ths-CRP contribute to the diagnosis and curative for patients with CHF.
出处
《国际检验医学杂志》
CAS
2013年第15期1965-1966,1968,共3页
International Journal of Laboratory Medicine
关键词
心力衰竭
利钠肽
脑
肌钙蛋白T
C反应蛋白质
heart failure
natriuretic peptide
brain
tropnin T
C-reactive protein
