期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

舒芬太尼复合盐酸右美托咪定用于脊柱手术术后镇痛疗效观察 被引量：4

暂未订购
导出
摘要 目的:观察舒芬太尼复合右美托咪定在脊柱手术术后镇痛的效果。方法:选取择期全麻脊柱手术自愿行经静脉患者自控镇痛(PCIA)患者40例,随机分为对照组和实验组,对照组给予生理盐水+舒芬太尼+止吐药静脉自控镇痛;实验组给予生理盐水+舒芬太尼+右美托咪定+止吐药静脉术后自控镇痛。观察患者术后48 h内疼痛视觉模拟评分法(VAS)评分,镇静评分标准(Ramsay)分级及不良反应的情况。结果:术后疼痛VAS评分实验组优于对照组(P<0.05),Ramsay分级差异无统计学意义,术后恶性呕吐发生率实验组明显低于对照组(P<0.05)。结论:舒芬太尼复合右美托咪定用于胸科手术术后静脉镇痛效果更好,且不良反应更少。
作者 王明全 吴爱玲 颜渊
机构地区 内江市第一人民医院
出处 《临床医药实践》 2013年第9期671-673,共3页 Proceeding of Clinical Medicine
关键词 右美托咪定 舒芬太尼 脊柱 术后镇痛
分类号 R614 [医药卫生—麻醉学]
  • 相关文献

参考文献5

二级参考文献31

  • 1王庆,王珊娟,杭燕南.老年高血压患者围术期动态血压和动态心电图变化的临床研究[J].临床麻醉学杂志,2004,20(8):462-464. 被引量：36
  • 2Stemp LI, Karras GE Jr. Dexmedetomidine facilitates withdrawal of ventilatory support [ J ]. Anesthesiology,2006 ; 104 (4) : 890.
  • 3Angst MS, Ramaswamy B, Davies MF, et al. Comparative analgesic and mental effects of increasing plasma concentrations of dexmedetomidine and alfentanil in humans[J].Anesthesiology ,2004 ; 101 ( 3 ) :744-52.
  • 4Lin TF, Yeh YC , Lin FS, et al. Effect of combining dexmedetomidine and morphine for intravenous patient-controlled analgesia [J]. Br J Anaesth, 2009;102(1) :117-22.
  • 5Martin E, Ramsay G, Mantz J, et al. The role of the α2-adrenoceptor agonist dexmedetomidine in postsurgical sedation in the intensive care unit [J]. J Intensive Care Med,2003;18(1 ) :29-41.
  • 6MacDonald E, Scheinin M. Distribution and pharmacology of alpha 2-adrenoceptors in the centrol nervous system[ J]. J Physiol Pharmacol, 1955; 46(3) :241-58.
  • 7Ebert TJ, Hall JE, Barney JA, et al. The effects of increasing plasma concentrations of dexmedetomidine in humans [ J ]. Anesthesiology, 2000 ; 93 (2) :382-94.
  • 8Gerlach AT, Murphy CV. Dexmedetomidine-associated bradycardia progressing to pulseless electrical activity : case report and review of the literature [J]. Pharmacotherapy ,2009 ;29 (12) : 1492.
  • 9Tobias JD. Bradycardia during dexmedetomidine and therapeutic hypothermia[J]. J Intensive Care Med ,2008 ;23 ( 6 ) :403-8.
  • 10Rcangeli A, Gaspari R. Dexmedetomidine use in general anaesthesia [J]. Curr Drug Targets.2009,10(8):687-95.

共引文献92

同被引文献38

  • 1Kiribayashi M,Inagaki Y,Nishimura Y,et al. Caudal block- ade shortens the time to walking exercise in elderly pa- tients following low back surgery[J]. J Anesth,2010,24(2) : 192-196.
  • 2Kajiyama S, Niihata T, Suqimoto Y,et al. Postoperative pain management by intravenous patient -controlled analgesia in patients undergoing upper abdominal gastrointestinal sugery[J]. Masui, 2012,61 (10) : 1064.
  • 3Yie JC,Yang JT,Wu CY, et al. Patient -controlled anal- gesia? PCA following video-assisted thoracoscopic lobec- tomy comparison of epidural PCA and intravenous PCA[J] Acta Anaesthesiol, 2012,50 (3) : 92-94.
  • 4Jean LJ,Eric A J, Daniel LS. Spinal mechanisms con- tribute to analgesia produced by epidural sufentanil combined with bupivacaine for postoperative analgesia[J] Anesth Analg, 2003,97 (5) : 1446-1451.
  • 5Sakurai Y, Obatat, Odakaa,et al. Buccal administration of dexmedetomidine as a preanesthetic in children[J]. J Anesth, 2010,24(1) :49-53.
  • 6Yildiz M, Tavlan A, Tuncer S, et al. Effect of dexmedeto- midine on haemodynamic responses to laryngoscopy and intubation:Perioperative haemodynamics and anaesthetic requirements[J]. Drugs RD, 2006,7( 1 ) : 43-52.
  • 7Arain SR,Ruehl ow RM,Uhrich T D,et al. The efficacy of dexmedetomidine versus morphine for post operative analgesia after major inpatient surgery[J]. Anesth Analg, 2004,98(2) : 153-158.
  • 8Massad IM, Mohsen WA, Basha AS,et al. A balanced anesthesia with dexmedetomidine decreases postoperative nausea and vomiting after laparoscopic surgery[J]. Saudi Med J,2009, 30(8) : 1537-1541.
  • 9蔡明,楚敏.氯诺昔康对腹腔镜胆囊切除术超前镇痛的临床观察[J].中国医院药学杂志,2008,28(5):380-382. 被引量：9
  • 10唐贞申,张兵,安建雄,马银娜,冷火萍,梅晓辉,张炳熙.舒芬太尼皮下PCA用于术后镇痛的可行性研究[J].医学研究杂志,2008,37(9):49-51. 被引量：7

二级引证文献26

临床医药实践
2013年 第9期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部