摘要
目的研究影响慢性乙型重型肝炎患者预后的重要因素,并建立预后评估模型。方法收集2009年1月至2012年1月常州市第三人民医院确诊为慢性乙型重型肝炎的100例患者的临床资料和实验室数据,进行单因素和多因素的Logistic回归分析。结果单因素分析显示,存活组和死亡组患者的总胆红素(TBil)、凝血酶原时间(PT)、谷氨酰转肽酶(γ-GT)、血清总胆固醇、血清钠浓度、血小板(PLT)差异有统计学意义(P<0.05);多因素分析显示该病的预后与TBil、PT、γ-GT和PLT有关。结论γ-GT、TBil、PT和PLT可作为慢性乙型重型肝炎患者预后的判定因素,对临床有指导价值。
Objective To analyze the factors which may affect the prognosis of severe chronic hepatitis B, and to develop a prognostic model. Methods From January 2009 to January 2012, 100 in-patients with chronic severe hepatitis B of the Third People＇s Hospital of Changzhou were selected. The main clinical and laboratory variables were analyzed as predictive factors of survival with Logistic univariate and multivariate regression. Results Univa- riate analysis indicated TBil, PT, r-GT CHO, Na ＋ and PLT were significantly different between the survival group and death group（ P 〈0.05 ）. Multivariate analysis indicated that the prognosis of the disease was correlated with TBil,PT,r-GT and PLT. Conclusion Levels of r-GT,TBiI,PT and PLT can be used as predicting factors for the prognosis of patients with severe chronic hepatitis B ,which have guidance value for the clinical practice.
出处
《医学综述》
2013年第17期3215-3216,共2页
Medical Recapitulate
关键词
慢性乙型肝炎
预后
因素
Chronic hepatitis B
Prognosis
Factors
