摘要
目的:研究黔产药用植物忽地笑中的化学成分。方法:采用多种色谱手段和重结晶等方法,分离纯化化合物;根据化合物的理化性质和波谱数据鉴定其结构。结果:从忽地笑鳞茎95%乙醇提取物的粗碱部位中分离得到7个单体化合物,均为生物碱,分别被鉴定为石蒜碱(lycorine,1),二氢石蒜碱(dihydrolycorine,2),加兰那敏(galanthamine,3),力可拉敏(lycoramine,4),那维定(narwedine,5),lycoraminone(6)和2-羟基-6-甲氧基香水仙灵(2-hydroxyl-6-O-methyloduline,7)。结论:化合物5、6和7均为首次从该植物中分离得到。
Objective：To study the chemical constituents of Lycoris aurea from Guizhou province. Methods：All compounds were isolated and purified by by means of classic phytochemistry method and recrystallization. Their structures were identify by various spectral data and their physical characters. Results：Seven compounds （1-7）were isolated from the crude alkaloids extract of 95%ethanol of the material. Their structures were identified as lycorine（1）,dihydrolycorine（2）,galathanmine（3）,lycoramine（4）,narwedine（5）, lycoraminone（6）and 2α-methoxy-6-O-ethyloduline（7）. Conclusion：Compounds 5,6 and 7 were isolated from Lycoris aurea for the first time.
出处
《北方药学》
2013年第9期1-2,50,共3页
Journal of North Pharmacy
基金
国家973计划支撑项目(2012CB722601)
关键词
石蒜科
石蒜属
忽地笑
化学成分
生物碱
Amaryllidaceae Lycoris Lycoris aurea Chemical constituents Alkaloid
