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肾移植后停用激素行免疫维持治疗的临床分析

Withdrawal of steroid in kidney transplantation recipients
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摘要 目的 :探讨肾移植患者避免长期使用激素的可能性。方法 :对 9例联合应用 FK50 6及骁悉 (MMF)的肾移植患者于术后 6~ 8个月停用激素 ,并进行了随访。结果 :9例患者无急性排斥反应发生 ,大多数激素引起的症状改善。结论 :在 FK50 6和 MMF的基础上逐渐停用激素是安全的。 Purpose:To avoid using steroid in long term and decrease its side effects.Methods:We analyzed the data of 9 cases of patients whose immunosuppressive therapy were based on FK506 and MMF. Steroid has been withdrawn in 6 to 8 months after kidney transplantation.Results:All patients have been followed-up. The results indicated that no patient exhibited any acute rejection episode, and the side effects of steroid were diminished.Conclusions:We believe that withdrawal of steroid on basis of FK506 and MMF may be safe, and further investigations are necessary.
出处 《临床泌尿外科杂志》 2000年第10期439-440,共2页 Journal of Clinical Urology
关键词 肾移植 免疫抑制剂 激素 免疫维持治疗 Kidney transplantation Immunosuppressive agents Steroid
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参考文献3

  • 1DonaldE,ChristopherC,JeffreyL,etal.Withdrawalofsteroidsafterrenaltransplantation-clinicalpredictorsofoutcome.Transplanation,1992,53:41~46
  • 2HricikDE.Steroidwithdrawalinrenaltransplantrecipi-ents:propointofview.TransplantProc,1998,30:1380~1385
  • 3YagisawaT,NakadaT,HiromasaY.etal.Successfulsteroidwithdrawalhalfayearafterkidneytransplanta-tion.IntUrolNephrol,1995,27:495~499

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