摘要
目的观察类风湿关节炎(RA)不同中医证型与一些理化指标之间的相互关系,为临床诊疗提供实验基础。方法回顾性分析天津中医药大学第二附属医院2010年9月至2011年11月门诊及住院76例RA患者的各项实验室检查指标及中医辨证分型,对34例寒湿痹阻、13例湿热痹阻、17例肝肾阴虚、12例痰瘀痹阻四种主要单一证型的DAS28、红细胞沉降率(ESR)、C反应蛋白(CRP)、类风湿因子(RF)、抗环瓜氨酸肽抗体(anti-CCP)和抗角蛋白抗体(AKA)的结果进行统计学分析。结果 DAS28湿热痹阻型与其他三种证型相比差异均有统计学意义,痰瘀痹阻型和肝肾阴虚型之间差异有统计学意义,而寒湿痹阻型和痰瘀痹阻型之间以及寒湿痹阻型和肝肾阴虚型之间差异无统计学意义;湿热痹阻型的RA患者ESR、CRP显著高于其他三种证型RA患者(P<0.01),而RF、anti-CCP、AKA结果在以上四型RA中的差别无统计学意义。结论 RA早期或活动期中医症候主要为湿热痹阻型,活动性和炎症程度最高。
Objective To observe the relationship between TCM syndromes and some laboratory indicators of rheumatoid arthritis（RA） patients,and to supply experiment base for clinical practice.Methods Retrospective analytical method was used to investigate pattern distribution and main laboratory indicators of 76 patients from the Second Affiliated Hospital of Tianjin University of TCM during Sep.2010 and Nov.2011.DAS28 score,ESR,CRP,RF,anti-CCP and AKA of 34 cold-damp impeding pattern,13 damp-heat impeding pattern,17 liver kidney yin deficiency and 12 sputum-silting impeding pattern were selected to perform statistics analysis.Results There were great differences in DAS28 score among damp-heat impeding pattern and other three patterns,and sputum-silting impeding pattern and liver kidney yin deficiency pattern.But there was no statistical significance between cold-damp impeding pattern and sputum-silting impeding pattern,cold-damp impeding pattern and liver kidney yin deficiency pattern.The levels of ESR,CRP of RA patients of the damp-heat impeding pattern were significantly higher than the other three patterns（P 0.01）.But the differences in level of RF,anti-CCP,AKA were of no statistical significance between the four patterns.Conclusion The early or active stage of RA is mainly damp-heat impeding pattern of TCM syndrome,with the highest activity and inflammation degree.
出处
《医学综述》
2013年第16期3063-3065,共3页
Medical Recapitulate
关键词
类风湿关节炎
中医证型
实验室指标
Rheumatoid arthritis
TCM syndrome
Laboratory indicator
