摘要
目的探讨红细胞分布宽度(RDW)对预测慢性心力衰竭死亡率的价值。方法检索PubMed、Embase、CNKI数据库中所有论述RDW与慢性心衰死亡率队列研究的文献,使用Stata12.0软件计算合并死亡率的风险比(HR)和95%可信区间(95%CI)。结果共纳入相关文献6篇,累计样本量13502例。对入选文献进行一致性检验,文献间具有异质性(I2=79.9%,P<0.001),采用随机效应模型合并显示高水平RDW慢性心力衰竭患者死亡风险更高(HR=1.18,95%CI:1.10~1.25,P<0.001)。结论RDW是预测慢性心力衰竭死亡率的指标。
Objective To investigate the predictive value of red cell distribution width (RDW) to the mortality of chronic heart failure (CHF). Methods The databases of PubMed, Embase and CNKI were retrieved to collect the studies about the relationship between RDW and the mortality of CHF. The hazard ratio (HR) and 95%confidence interval (CI) of the mortality of CHF were calculated by using Stata12.0 software. Results There were totally 6 studies included involved 13 502 cases. The analysis on homogeneity showed that all eligible studies had heterogeneity (I2=79.9%, P〈0.001). The combined HR was 1.18 (95%CI:1.10-1.25, P〈0.001) after using random effect model. Conclusion RDW is an index for predicting the mortality of CHF.
出处
《中国循证心血管医学杂志》
2013年第4期349-351,共3页
Chinese Journal of Evidence-Based Cardiovascular Medicine
基金
全军后勤科研"十二五"重大课题分题(AWS11Z006)