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苦参中黄酮类成分薄层色谱鉴别研究 被引量：5

Identification of Flavonoids in Sophora flavescens by Thin-layer Chromatography
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摘要 目的:研究苦参的薄层色谱鉴别特征,建立苦参薄层色谱鉴别的专属性方法。方法:采用乙酸乙酯为提取溶剂,超声处理样品,硅胶G板分离鉴别苦参中黄酮类成分。结果:薄层色谱检出苦参酮、苦参醇Ⅰ、三叶豆紫檀苷、高丽槐素和槐属二氢黄酮G,色谱斑点清晰,能有效提供苦参的鉴别特征。结论:方法可行,重复性好,专属性强,为完善苦参薄层鉴别方法提供了实验资料和科学依据。 Objective： To develop an exclusive identifying method for Sophora flavescens by thin-layer chromatography （TLC）. Methods： The experiments were performed on the plates of silica gel G by using general developing agents. Results： The constituents of flavonoids （ trifolirhizin, maackiain, kushenol I, kurarinone, sophoraflavanone G ）in Sophora flavescens were separated and identified respectively. Conclusion： The method is practicable repeatable, and exclusive, could be adopted as a standard for the quality control of Sophora flavescens.
作者 马鸿雁 朱雅玲 杜憬生 李娟 杨全
机构地区 广东药学院中药学院 广东省中医院
出处 《中国现代中药》 CAS 2013年第8期659-661,共3页 Modern Chinese Medicine
基金 广东省高校优秀青年创新人才培养计划项目(LYM11079)
关键词 苦参 黄酮 薄层色谱 Sophora flavescens Flavonoids TLC
分类号 R286.0 [医药卫生—中药学]
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参考文献8

  • 1国家药典委员会.中国药典[S].—部.北京:中国医药科技出版社,2010:155.
  • 2顾关云,肖年生,蒋昱.苦参的化学成分、生物活性和药理作用[J].现代药物与临床,2009,24(5):265-271. 被引量：53
  • 3Han J, Sun M, Cui Y, el al. Kushen flavonoids induceapotosis in tumor cells by inhibition of NF-kappaBactivation and multiple receptor tyrosine kinase activities[J], phytother Res,2007,21 (3) :262-268.
  • 4Berghe W V, De Naeyer A, Dijsselbloem N, et al.Attenuation of ERK/RSK2-driven NF-kappaB geneexpression and cancer cell proliferation by kuarinone, alavandulyl flanone isolated from Sophora Jlavescens Ait.Roots [ J ]. Endocr Metab Immune Disorder Drug Targets,2011,11(3) :247-261.
  • 5Oh I,Yang W Y,Chung S C, et al. In vitro sortase Ainhibitory and antimicrobial activity of flavonoids isolatedfrom the roots of Sophora flavescen [ J]. Arch Pharm Res,2011,34(2):217-222.
  • 6Jin J H, Kim J S, Kang SS, et al. Anti-inflammatory andanti-arthritic activity of total flavonoids of the roots ofSophora flavescens [ J] . J Ethnopharmacol, 2010,127 ( 3 ):589-595.
  • 7Cha J D,Moon S E,Kim J Y,et al. Antibacterial activity ofsophoraflavanone G isolated from the roots of Sophoraflavescens against methicillin-resistant Staphylococcusaureus[ J]. Phytother Res,2009,23(9) : 1326-1331.
  • 8Cha J D,Jeong M R,Jeong S I,et al. Antibacterial activityof Sophoraflavanone G isolated from the Roots of Sophoraflavescens [ J ]. J Microbiol Biotechnol, 2007, 17 ( 5 ):858-864.

二级参考文献49

  • 1Shen C C,Lin T W, Huang Y L, etal. Phenolic constituents of the roots of Sophora flavescens[J].J Nat Prod, 2006,69 (8) : 1237-1240.
  • 2Ding P L,Hou A T, Chen D F. Three new isoprenylated flavonoids from the roots of Sophora flavescens[J]. Asian Nat Prod Res, 2005,7(3) :237-243.
  • 3Ma X C,Xin X L, Zhang B J, et al. Structure determination of flavonoids from Sophora flavescens [J]. Magn Reson Chem, 2008,46(9): 903 -906.
  • 4Li K, Wang H. Simultaneous determination of matrine sophridine and oxymatrine in Sophora flavescens Air. by high performance liquid chromatography[J]. Biomed Chromatogr, 2004,18(3) : 178-182.
  • 5Chen X, Yi C, Yang X, Liquid chromatography of active principles in Sophore flavescens root[J]. J Chromatogr B Analyt Technol Biomed Life Sci,2004,812(1/2):149-163.
  • 6Ling J Y, Zhang G Y, Cui Z J, etal. Supercritical fluid extraction of quinolizidine alkaloids from Sophora flavescens Ait. and purification by high-speed counter-current chromatography [J]. J Chromatogr A,2007,1145(1/2) :123-127.
  • 7Wang S, Qu M, Cheng Y. NACE-ESI-MS combined with on-line concentration for high-sensitivity analysis of quinolizidine alkaloids [J]. Electrophoresis, 2007,28(9) : 1399-1406.
  • 8Yoo H H, Kim T, Ahn S, etal. Evaluation of the estrogenic activity of Lequminosae plants[J].Biol Pharm Bull, 2005, 28(3) : 538-540.
  • 9Hillerns P I, Wink M. Binding of flavonoids from Sophora flavescens to the rat uterine estrogen receptor [J]. Planta Med, 2005,71(11) :1065-1068.
  • 10Sato S, Takeo J, Aoyama C, et al. Na^+-glucose cotransporter(SGLT) inhibitroy flavonoids from the roots of Sophora flavescens[J]. Bioorg Med Chem, 2007, 15 ( 10):3445-3449.

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中国现代中药
2013年 第8期

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