摘要
以正丁醇与水杨酸为原料,采用对氨基苯磺酸为催化剂,通过酯化反应合成了水杨酸正丁酯。考察了酸醇物质的量比、催化剂用量、反应时间对水杨酸正丁酯化收率的影响。结果表明,在回流条件下,当水杨酸的加入量0.20 mol,正丁醇的加入量0.32 mol,即酸与醇物质的量比为1∶1.6,催化剂对氨基苯磺酸用量为0.70 g(相当于5%的酸),反应4.0 h时,水杨酸正丁酯收率可达到72.90%。
Synthesis of butyl salicylate from 2-hydroxybenzoic acid and n-butanol catalyzed by p-aminobenzene sulfonic acid was studied.The effects of the molar ratio of 2-hydroxybenzoic acid to n-butanol,the amount of catalyst and the reaction time on the yield was discussed.The results show that when the molar ratio of 2-hydroxybenzoic acid（0.20 mol） to n-butanol（0.32 mol） was 1 ∶ 1.6;the amount of catalyst was 0.70 g（5%,with respect to 2-hydroxybenzoic acid） and the reaction time was 4.0 h under reflux,the yield of butyl salicylate reached 72.90%.
出处
《应用化工》
CAS
CSCD
2013年第8期1426-1427,1431,共3页
Applied Chemical Industry
基金
宝鸡文理学院重点项目(ZK12016)
关键词
水杨酸
正丁醇
对氨基苯磺酸
2-hydroxybenzoic acid
n-butanol
p-aminobenzene sulfonic acid
