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维生素E与阻塞性睡眠呼吸暂停低通气综合征的相关性研究 被引量:1

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摘要 目的通过检测阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apnea-hypopnea syndrome,OSAHS)患者体内维生素E(Vit E)水平的变化,探讨OSAHS患者体内抗氧化能力的变化及意义。方法随机选择OSAHS患者(OSAHS组)及健康人(对照组),每组30例,2组间体重指数、年龄、性别比均差异无统计学意义(P>0.05)。所有入选者在夜间入睡前及晨起5 min内(睡眠监测结束后)抽取空腹肘静脉血约4 ml,用比色法测定Vit E水平,并记录呼吸睡眠事件有关的监测指标。结果与对照组比较,OSAHS患者睡前及晨起Vit E水平均明显下降(P<0.05),OSAHS组睡前与晨起Vit E水平差异无统计学意义(P>0.05)。Vit E水平与反应OSAHS严重程度的指标呈负相关(P<0.05)。结论 OSAHS患者出现抗氧化能力下降,其抗氧化能力下降是持续存在的,抗氧化能力下降与OSAHS严重程度密切相关。
出处 《河北医药》 CAS 2013年第18期2775-2776,共2页 Hebei Medical Journal
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