摘要
目的 观察脊髓损伤 (SCI)后局部组织中多种离子含量的变化。方法 20只 SD大鼠随机分为对照组及损伤组 (n=4),采用原子吸收光谱法测定损伤后 1、 4、 8和 24h局部组织中 Ca2＋、 K＋、 Na＋、 Zn2＋、 Mg2＋和 Cu2＋含量变化。结果 SCI后局部组织中 Ca2＋、 Na＋离子浓度较对照组明显升高
Objective To detect the change of ions content after spinal cord injury.Method Following a controlled compression injury to the thoracic spinal cord(T8.9).rats were sacrificed at 1,4,8and 24hour points(n=4).The injuried segments were resected The ions (Ca2＋ ,K＋ ,Na＋ ,Zn2＋ ,Mg2＋ andCu2＋ )were measured with atomic absorption spectrophotomertry. Result In the injuried tissue,there is a significant increase in Ca2＋、 Na＋ ,and decrease in K＋、 Mg2＋ .Conclusion The change of ions contents are important morpholehical events in the secondary injury period after spinal cord injury.It may be the comman channal for the differrent cells death.
出处
《现代康复》
CSCD
2000年第11期1684-1684,共1页
Modern Rehabilitation
基金
上海市科委基金赞助 NO.97XD14015
关键词
脊髓损伤
离子
坏死
凋亡
spinal cord injury (SCI)
ion
necrosis
apoptosis
