摘要
背景:直接测量颈椎管容积和颈脊髓体积可以较全面、立体地反映颈椎管对颈段脊髓的包容情况,尸体标本石蜡灌注法、树脂灌注法和有限元模型法均具参考价值,但操作繁复,且较难应用于临床,目前尚缺乏能够准确测量颈脊髓体积和颈椎管容积的简便测量方法。目的:探讨颈椎管容积与颈脊髓体积比值与脊髓型颈椎病(CSM)临床症状的相关性。方法:根据JOA评分将CSM患者分为A组(轻度)31例及B组(中重度)27例,所有患者均接受颈椎MRI扫描并计算颈椎管容积与颈脊髓体积比值,对两组患者的颈椎管容积与颈脊髓体积比值进行独立样本t检验,对两组患者的颈椎管容积与颈脊髓体积比值和JOA评分进行相关性分析。结果:A组患者的颈椎管容积与颈脊髓体积比值明显大于B组(t=15.094,P=0.001);B组患者的颈椎管容积与颈脊髓体积比值与JOA评分的决定系数(r2=0.738)高于A组(r2=0.563);颈椎管容积与颈脊髓体积比值与JOA评分的线性回归趋势提示A、B两组患者的颈椎管容积与颈脊髓体积比值均与JOA评分呈正相关。结论:颈椎管容积与颈脊髓体积比值可以反映颈椎管对颈脊髓的包容状态,利用MRI测量颈椎管容积与颈脊髓体积比值可以定量反映脊髓的损害程度。
Background：Measuring the volume of the cervical spinal canal and the cervical spinal cord directly can comprehensively and vividly reflect the inclusive status of the cervical spinal canal to the cervical spinal cord.The methods of paraffin perfusion in the cadaver,resin infusion and finite element model,though have reference value,are very complicated and difficult to apply in clinic.Therefore,there still lack some easy ways to accurately measure the volume of cervical spinal cord and cervical spinal canal.Objective：To investigate the relationship between the severity of cervical spondylotic myelopathy（CSM） and the ratio of the cervical spinal canal volume to the cervical spinal cord volume.Methods：Divide the patients with CSM into 2 groups according to the Japanese Orthopaedic Association（JOA） scores.Group A（mild） has 31 patients and group B（moderate to severe） has 27 patients.Perform the MRI（Magnetic Resonance Imaging） scan on each patient and calculate the ratios of the cervical spinal canal volume to the cervical spinal cord volume.Conduct independent-sample T test on each ratio of the 2 groups.And analyze the correlation between the ratios and the JOA scores.Results：Ratios of the cervical spinal canal volume to the cervical spinal cord volume of group A are significantly higher than that ratios of group B（t=15.094,P=0.001）;While the coefficient of determination of that ratios of group B and JOA scores（r2 =0.738） is higher than that of group A（r2 =0.563）;The linear regression trend of the ratio of the cervical spinal canal volume to the cervical spinal cord volume and the JOA scores shows that this ratio has positive correlation with JOA scores.Conclusions：The ratio of the cervical spinal canal volume to the cervical spinal cord volume can reflect the inclusive status of the cervical spinal canal to the cervical spinal cord.Adopting MRI in measuring this ratio can quantitatively reflect the damage extent of the spinal cord.
出处
《中国骨与关节外科》
2013年第3期243-246,共4页
Chinese Journal of Bone and Joint Surgery
关键词
脊髓型颈椎病
容积
MRI
cervical spondylotic myelopathy
volume
MRI
