摘要
目的:探讨血浆置换术对孕妇血清中IgG抗体及血液内环境的影响。方法:对109例抗人球蛋白法测定抗体效价高于1:64的孕妇,在血浆置换术前后,进行IgG抗体的表达水平及血液中RBC、Hb和HCT量的变化检测。结果:所有孕妇在血浆置换术后IgG含量均有不同程度的降低,而RBC、Hb和HCT量均有不同程度的提高。血浆置换术后1年,除1例在早产后死亡外,其他108例未发生新生儿溶血病。结论:采用血浆置换以及补足新鲜血浆的手段,可明显降低IgG抗体表达,并能防止置换后贫血症的发生。
Objective：To discuss effects of plasmaphresis to IgG antibody and environment of blood in pregnant women.Method：A total of 109 pregnant women who had been confirmed that the globulin antibody titers were higher than 1：64 were treated with plasmaphresis.After plasmaphresis,the IgG antibody,RBC,Hb and HCT changes from serum of the pregnant women were determined.Result：After plasmaphresis,the 109 women showed different levels descend of IgG concentration.Meanwhile,the RBC,Hb and HCT had different levels arise.Despite one dead case because of premature labour,the 108 cases were not appeared hemolytic disease of newborn disease after the treatment in one year.Conclusion：Plasmaphresis with complement of fresh plasma could significantly decrease IgG antibody and prevent anemia after serum exchange.
出处
《临床血液学杂志（输血与检验）》
CAS
2013年第4期525-526,530,共3页
Journal of Clinical Hematology(Blood Transfusion & Laboratory Medicine)
