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年龄因素对临床血小板输注影响的分析 被引量:11

Study on impact of recipients age on clinical platelets transfusion
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摘要 目的:探讨年龄因素对临床血小板输注所产生的影响。方法:对72例需要输注血小板的患者做输注前及输注后24h外周血血小板计数,计算血小板增加修正值以评价输注效果。结果:年龄≤30岁、>30~≤50岁、>50~≤70岁、>70岁的4组患者血小板输注无效率分别为19.0%、43.6%、60.3%、41.7%;50岁以上患者中部分输注前血小板计数值较高,而其输注后的血小板增加量并不明显。结论:总体上血小板输注无效率随年龄的增加而增加,部分原因是大龄患者在血小板计数较高时就进行输注,反而效果不明显。 Objective:To investigate the influence of patients' age on the effect of platelets transfusion.Method:Peripheral blood platelets of 72 patients required platelet transfusion were counted 24 hours before and after each infusion.Corrected count increment was calculated to evaluate the effect of platelet transfusion.Result:The platelet transfusion refractoriness(PTR)rate of each group was 19.0%(age≤30),43.6%(age 31 to 50),60.3%(age 51 to 70)and 41.7%(age〉70).And platelet level before infusion of some patients over 50 years old was found to be higher than the average while the corresponding post-transfusion platelet increments were not obvious as others.Conclusion:The occurrence of PTR is generally increased with age,partially because platelet transfusion is carried out for elderly patients when their platelets are still at a high level.
出处 《临床血液学杂志(输血与检验)》 CAS 2013年第4期513-515,共3页 Journal of Clinical Hematology(Blood Transfusion & Laboratory Medicine)
基金 上海市公共卫生重点学科建设计划资助项目(No:12GWZX0202)
关键词 血小板输注 年龄 血小板增加修正值 输注后血小板增加量 platelet transfusion age corrected count increment post-transfusion platelet increment
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