摘要
目的 探讨恶性血液病患者血瘀证的临床意义。方法 对 112例恶性血液病患者进行了血瘀证的临床观察和血浆血小板α颗粒膜蛋白 (GMP - 140 )及D -二聚体 (D -D)的检测。结果 恶性血液病患者中血瘀证的检出率为 6 9.6 4%。血瘀证组血浆GMP - 140及D -D检测的水平均显著高于非血瘀证组 (P <0 .0 1)。结论 恶性血液病血瘀证患者血小板的激活与消耗增多 ,并有继发性纤溶存在。血浆GMP - 140及D
OBJECTIVE To study the clinical significance of blood stasis in malignant blood diseases. METHODS In 112 patients with malignant blood diseases, the symptoms and signs of blood stasis were observed and the contents of platelet α-granule membrane protein in plasma (GMP140) and Ddimer (DD) were detected. RESULTS 69.64% of the patients showed blood stasis. Those showing blood stasis had higher levels of GMP140 and DD than those who did not show blood stasis (P<0.01). CONCLUSION In the patients with blood stasis of malignant blood diseases, more platelets are activated and consumed, and there exists secondary fibrinolysis. The levels of plasma GMP140 and DD are closely related to the manifestations of blood stasis.
出处
《南京中医药大学学报》
CAS
CSCD
2000年第3期146-147,共2页
Journal of Nanjing University of Traditional Chinese Medicine
基金
江苏省科委自然科学基金!(BK99164)
关键词
恶性血液病
血瘀证
D-二聚体
GMP-140
研究
诊断
blood stasis
malignant blood disease,
platelet α-granule membrane protein in plasma
D-dimer
