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肺功能在诊断支气管哮喘合并慢性阻塞性肺疾病中的应用 被引量:13

Application of spirometry in diagnosis of asthma-chronic obstructive pulmonary disease overlap syndrome
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摘要 支气管哮喘(简称哮喘)和慢性阻塞性肺疾病(COPD)在临床实践中具有部分共存现象.该类患者的病史、临床体征、辅助检查等方面与单纯COPD的患者有许多相似之处,但哮喘合并COPD患者在生活质量、疾病的严重程度、死亡风险、经济负担和治疗措施等方面均与单纯COPD患者有所不同,如何鉴别支气管哮喘合并COPD与COPD患者成为临床医师亟待解决的问题.目前肺功能检查作为呼吸系统最常用的检查手段,其中MMEF、FEV1、气道阻力、气道反应性、弥散功能等内容在这两项疾病的鉴别中具有重要的意义,且肺功能检查具有无创、简便、准确等优势,对肺功能的进一步研究可使它在诊断哮喘合并COPD中发挥更大的作用. In clinical practice,bronchial asthma (asthma) and chronic obstructive pulmonary disease (COPD) may coexists in particular patients.Those people who with asthma COPD overlap syndrome have many similarities with typical COPD patients in medical history,clinical sign,assistant examination and so on.But there are many differences in other aspects,such as the quality of life,severity of the disease,mortality risk,economic burden and treatment measures.Therefore,it becomes an urgent problem to identify the patients with typical COPD from those with overlap syndrome for clinicians.Now it found that spirometry as the most important test in respiratory system,the items like MMEF,FEV1,airway resistance,airway responsiveness and diffusing capacity in pulmonary function testing has significance in identifying these two kinds of diseases.Moreover,spirometry has its advantages,which is non-invasive,simple,convenient and accurate.By further study on spirometry,it can play a greater role in diagnosis of asthma-COPD overlap syndrome.
出处 《国际呼吸杂志》 2013年第13期1003-1005,共3页 International Journal of Respiration
基金 浙江省教育厅项目资助(Y200908688) 浙江省中医院院级课题资助
关键词 支气管哮喘 慢性阻塞性肺疾病 肺功能 Bronchial asthma Chronic obstructive pulmonary disease Spirometry
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