摘要
目的 :观察双花喷雾剂治疗小儿上呼吸道感染的疗效 ,探讨其作用机理。方法 :将 2 76例患儿随机分为两组 ,治疗组用双花喷雾剂 ,对照组用双黄连气雾剂 ;动物实验观察双花喷雾剂抗炎、抗病毒作用。结果 :双花喷雾剂治疗总有效率 99 0 3% ,痊愈率 65 38% ;对照组总有效率 94 11% ,痊愈率 4 4 12 % ,两组总有效率比较差异有显著性意义 (P <0 0 1) ,治疗组疗效优于对照组。实验研究表明 :双花喷雾剂能明显抑制二甲苯所致小鼠耳肿胀及蛋清引起的足趾肿胀 ;对小鼠肺内流感病毒增殖有明显抑制作用。结论 :双花喷雾剂具有明显抗炎、抗病毒作用 ,治疗小儿上呼吸道感染疗效好、作用快、安全可靠。
To study the effect and mechanism of Shuanghua aerosol (SHA) in treating infantile upper respiratory tract infection (IURTI). Methods: In the clinical study, 276 cases of IURTI were randomly divided into two groups. The treated group was treated with SHA and the control group was treated with Shuanghuanglian aerosol (SHLA). In the experimental study, the effect of SHA on anti-inflammatory and anti-viral were observed. Results: The clinical total effective rate of SHA was 99.03% and its cure rate 65.38%, while those of the SHLA was 94.11% and 44.12% respectively, significant difference was shown between the two groups (P<0 01). Experimental study showed that SHA could inhibit the xylol induced ear swelling and the egg white induced paw swelling in mice obviously, suppress the proliferation of influenza virus in rat′s lung. Conclusion: SHA has obvious anti-inflammatory and anti-viral effect, and has good curative effect in treating IURTI.
出处
《中国中西医结合杂志》
CAS
CSCD
北大核心
2000年第9期653-655,共3页
Chinese Journal of Integrated Traditional and Western Medicine
基金
河南省教委科技攻关项目!(No .95471 0 0 9)
关键词
双花喷雾剂
上呼吸道感染
中医药疗法
儿童
Shanghua aerosol, upper respiratory tract infection, external invaded Wind-Heat Syndrome, anti-viral effect
