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D-二聚体检测在肝脏疾病诊断中的意义 被引量:8

Clinical significance of D-dimer assay in patients with liver diseases
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摘要 目的 探讨D 二聚体在肝脏疾病中的临床意义。方法 用胶乳凝集试验 (LAT)检测血浆D 二聚体含量并比较其结果。结果 对 6 0例各类肝病进行了D 二聚体测定 ,其中包括急性黄疸性肝炎6例 ,慢性活动性肝炎 2 3例 ,肝硬化代偿期 2 5例 ,肝硬化失代偿期 3例 ,原发性肝癌 3例 ,其中阳性率分别为 5 0 %、34.78%、6 8%、10 0 %与 6 6 .6 6 %。结论 检测表明各类肝病呈现出不同程度的纤溶亢进现象及DIC 。 Objective To explore the clinical significance of D dimer in liver diseases.Methods Latex agglutinative test(LAT)was used in the detection of plasma D dimer.Results D dimer was assayed in 60 patients with various liver diseases.The result showed that 3 patients(50%)were positive of D dimer in 6 patients with acute icteric hepatitis,8(34.78%)in 23 with chronic active hepatitis,17(68%)in 25 with liver cirrhosis in compensatory stage and 3(100%) in 3 patients with liver cirrhosis in incompensatory stage,and 2(66.66%)in 3 patients with hepatocellular cancer respectively.Conclusion The different degrees of hyperfibrinolysis exist in the patients with various liver diseases, which is one of many complex causes of bleeding tendency in liver diseases complicated with primary hyperfibrinolysis of DIC,and the indications for anti fibrinolysis therapy were also discussed.
出处 《河北医药》 CAS 2000年第8期570-571,共2页 Hebei Medical Journal
关键词 肝脏疾病 D-二聚体 诊断 胶乳凝集试验 liver diseases D-dimer hyperfibrinolysis
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  • 1P. Montemurro,M. Conese,D. F. Altomare,V. Memeo,M. Colucci,N. Semeraro. Blood and tissue fibrinolytic profiles in patients with colorectal carcinoma[J] 1995,International Journal of Clinical & Laboratory Research(4):195~200

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