摘要
目的建立石墨炉原子吸收光谱法直接测定尿中铊的分析方法。方法用0.1%曲拉通稀释尿样,以硝酸钯为基体改进剂消除干扰,用工作曲线法定量,石墨炉原子吸收法直接测定尿中的铊。结果铊在0.0～50.0μg/L线性良好,相关系数为0.999 0,方法检出限0.12μg/L,高中低尿样铊含量日内精密度分别为2.1%、3.7%、3.3%,回收率97.6%～103.1%。结论用硝酸钯为基体改进剂,尿样经适当稀释,石墨炉原子吸收光谱法直接进样测定,该方法简单快速、精密度和稳定性很好,可以满足急慢性铊中毒者尿中铊含量的测定,为诊断和治疗提供参考依据。
[ Objective] To establish a method for the directly determination of thallium in urine by graphite furnace atomic absorption spectrometry. [ Methods ] The urine samples were diluted by 0.1% Triton, the palladium nitrate was used as the matrix modifier to eliminate the interference, the quantitative evaluation was conducted by working curve method, and the concentration of thallium in urine was directly determined by graphite furnace atomic absorption spectrometry. [ Results ] The linearity range of thalli- um was 0.0 - 50.0μg/L, and the correlation coefficient was 0.999 0, with the detection limit of 0.12μg/L. The intra-day preci- sion of high, medium and low concentration of urine sample was 2.1%, 3.7% and 3.3% respectively. The recovery rate was 97.6%-103.1%. [ Conclusion] While the palladium nitrate is used as the matrix modifier, the urine samples are diluted suitably, and the samples are determined directly by graphite furnace atomic absorption spectrometry, the method is simple and rapid, with good precision and stability, and suitable for thallium determination in urine of patients with acute and chronic thallium poisoning, which can provide a reference for the diagnosis and treatment.
出处
《职业与健康》
CAS
2013年第15期1906-1908,共3页
Occupation and Health
关键词
原子吸收光谱法
尿铊
测定
Graphite furnace atomic absorption spectrometry
Urinary thallium
Determination
