摘要
目的 探讨夜间无创伤通气在慢性阻塞性肺疾病(COPD)缓解期的应用及其机理.方法 将50例COPD缓解期患者随机分为治疗组与对照组,每组25例,观察夜间无创伤通气治疗前后12分钟步行距离(12MWD),血气分析、肺功能、膈肌移动度和夜间最低氧饱和度(SaO_2)的变化.结果 夜间无创伤通气治疗组治疗后12MWD、FVC%、FEV_1%、膈肌移动度夜间最低SaO_2均较对照组增高,PaCO_2较对照组降低且有显著差异(P<0.05).结论 夜间无创伤通气在COPD缓解期的康复治疗中非常重要,值得在临床上推广应用.
ve To study the curative effect of nocturnal noninvasive ventilation in chronic obstructivepulmonary disease (COPD) patients during convalescent phase. Methods The 50 stable COPD patients were dividedinto two groups in a randomized control study, the therapeutic group(25 cases) and the control group (25 cases). Inthe therapeutic and control group the data of 12MWD, FVC%, FEV1 %, blood gas analysis, diaphragm movementdegree and the lowest nocturnal SaO2 were measured before and after the investigation. Results In the therapeuticgroup, 12 MWD, FVC%, FEV1%, diaphragm movement degree, lowest nocturnal SaO2 and PaCO2 were markedlyimproved, there was significant difference between the therapeutic group and the control group(P < 0.05). Conclu-sion Nocturnal invasive ventilation plays a certain role in the rehabilitative treatment in COPD patients duringconvalescent phase. It is of great value in clinical treatment for COPD patients.
