摘要
目的：分析自闭症儿童的脑电图特点及β频带功率。方法：选择2008～2012年在我院脑电图室检查的自闭症患儿并设对照组，分析其脑电图特点及口频带功率。结果：38例2岁零3个月至8岁的患儿中，脑电图正常范围15例，非药物性β活动增多11例，背景活动慢化及节律失调5例；伴尖波、棘波7例，其中6例为局灶性放电，主要在中央、中后颞区，1例为少量阵发广泛性棘慢波。睡眠期额区尖形θ波2例；枕区α节律较同龄儿快1例。自闭症组额区β功率为（5．22±2．35）μV^2，中央区为（4．63±2．82）μV^2，对照组额区β功率为（4．49±2．07）μV^2，中央区为（3．29±2．07）μV^2，P〉0．05，差异无统计学意义。结论：自闭症患儿的脑电图常伴有不同类型的非特异性异常，明显高于正常儿童，主要表现为非药物性快波增多、局灶性痫样放电、背景节律慢化和节律失调等。自闭症患儿额、中央区β频带功率与对照组相比差异无统计学意义。
Objective： To analyze the EEG and beta power of children with autism. Methods： The patients with autism and the control group were involved in our EEG department from 2008 to 2012, so as to analyze the EEG characteristics and beta power. Results：Of all the 38 patients, 15 are normal. Non --pharmaceutical beta activity increased in 11 cases; the slow background activities and disrhythmia occurred in 5 cases. Spike and were showed in 7 cases, including local discharges in 6 cases, which were mainly found in central and temporal areas; Generalize spike and waves were showed in 1 case; Frontal sharp theta during sleep appeared in 2 cases; The alpha activity was faster than that of his age in one case;In both children with β power of autism and controls there was no statistical difference{ F3（5.22±2.35）μV^2 vs（4.49±2.07）μV^2 ,C3（4.63±2.82）μV^2 vs（3.29±2.07）μV^2,P〉0. 05}. Conclusion：Children with autism often have different types of non-specific EEG. It is higherthan that of normal children; most of them are increasing non-pharmaceutical beta activity or focal epileptic discharges or the background slow and disrhythmia. β power in frontal and central areas of autism and controls is no statisticaldifference .
出处
《癫痫与神经电生理学杂志》
2013年第4期226-229,共4页
Journal of Epileptology and Electroneurophysiology(China)
