摘要
目的:分析药品不良反应(ADR)发生的特点和报告质量,促进临床合理用药。方法:采用回顾性分析方法,对2012年1—12月武汉市东西湖区人民医院收集的165例ADR报告进行统计分析。结果:165例ADR报告中,由抗感染药引起的ADR居首位,为38.69%(65/168),其次为中药制剂,占19.64%(33/168);ADR的表现以皮肤及其附件的损害最为常见,占41.62%(82/197);ADR发生率最高的药物为参附注射液,其次为米索前列醇片;165例ADR中,有6例严重的ADR;我院ADR报告率偏低,存在漏报现象;新的、严重的ADR报告数较少。结论:应加大ADR监测和报告力度,做好ADR知识宣传,合理用药,减少或避免ADR的发生。
OBJECTIVE：To analyze the characteristics of adverse drug reactions （ADRs） and the quality of the ADR reporting so as to promote clinical rational use of drugs. METHODS： A total of 165 ADR cases collected in Wuhan Dongxihu District People＇ s Hospital during the Jan.-Dec. period of 2012 were analyzed retrospectively. RESULTS： Of the total 165 cases, anti-infective drugs-induced ADR cases took the lead with 38.69% （65/168） followed by Chinese patent medicine-induced ADR cases [ 19.64% （33/168）]. The ADRs manifested mostly as damage of skin and appendants [ 41.62% （82/197） ]. In terms of ADR incidence, Shenfu Injection took the lead followed by misoprostol tablets. Of the total 165 ADR cases, 6 were serious ADR cases. The rate of ADR reporting in our hospital was low and some ADRs were failed to be reported. There were less new or serious ADR cases. CONCLUSION： Great importance should be attached to ADR monitoring and reporting and publicizing to achieve rational use of drugs and reduce or avoid occurrence of adverse drug reactions.
出处
《中国医院用药评价与分析》
2013年第7期653-656,共4页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
药品不良反应
报告
分析
Adverse drug reaction
Report
Analysis
