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右旋美托咪定对右半肝切除术后全身麻醉苏醒期的影响 被引量:1

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摘要 目的探讨右半肝切除术中复合使用右旋美托咪定全身麻醉对肝癌患者术后麻醉苏醒期的影响。方法将70例拟行右半肝切除术的肝癌患者按随机数字表法分为2组,每组35例。麻醉诱导:2组患者均予阿托品0.5 mg、咪达唑仑0.05 mg.kg-1、利多卡因1 mg.kg-1、依托咪酯0.2 mg.kg-1、罗库溴铵0.08 mg.kg-1及芬太尼4μg.kg-1静脉注射,3 min后气管插管。确定插管成功后,机械通气,新鲜气流量为2.0 L.min-1,氧浓度为60%,调节潮气量8~10 mL.kg-1,呼吸频率10~12次.min-1,将呼吸末二氧化碳分压调至4.67~5.33 kPa。右旋美托咪定组在麻醉诱导前15 min开始静脉输注右旋美托咪定1μg.kg-1.h-1,至麻醉诱导时改为0.3μg.kg-1.h-静脉输注,直至关腹时停用。对2组患者手术时间、手术结束至患者睁眼的时间、拔管时间及术后躁动的情况进行比较。结果 2组患者手术时间及睁眼时间比较差异均无统计学意义(均P>0.05)。右旋美托咪定组的拔管时间及术后躁动发生率分别为(23.4±8.5)min及0.0%,对照组分别为(32.3±9.1)min及14.3%,2组比较差异均有统计学意义(均P<0.05)。结论右半肝切除术中应用右旋美托咪定后,患者术后拔管时间缩短,术后躁动发生率降低。
作者 金特特
出处 《实用临床医学(江西)》 CAS 2013年第5期44-45,62,共3页 Practical Clinical Medicine
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