摘要
目的:比较临床Ⅲ、Ⅳ期喉癌患者部分喉及全喉切除术后的生存情况。方法:回顾性分析我科行手术治疗的126例临床Ⅲ、Ⅳ期喉癌患者,用乘积限法进行生存分析,比较各因素与晚期喉癌术后患者生存率的关系。结果:126例患者中临床Ⅲ期80例,临床Ⅳ期46例。行部分喉切除术65例,行全喉切除者61例。126例患者中5年内共死亡24例,其中部分喉切除者15例,全喉切除者9例。部分喉切除术、全喉切除术5年生存率分别为62.58%、68.74%。2组患者生存曲线差异无统计学意义(P<0.05)。结论:对于晚期喉癌患者,在手术适应证掌握良好的前提下,可行部分喉切除术,其5年生存率与行全喉切除术者差异无统计学意义。
Objective：To compare the postoperative survival rate of laryngeal carcinoma patient at stage Ⅲ or Ⅳ whom accepted partial laryngectomy and total laryngectomy. Method：We performed a retrospective cohort follow up study of 126 patients of stage Ⅲ or Ⅳ who underwent operation for laryngeal carcinoma in Chinese PLA General Hospital between Junuary, 2005 and December, 2009. Survival rates were calculated by product-limit method. Result： There were 80 patients at stage Ⅲ and 46 patient at stage Ⅳ. Sixty five patients underwent partial laryngectomy and 61 patients underwent total laryngectoy. There were 24 patients in whole group died in the 5 years. 15 of them underwent partial and 9 accepted total laryngectomy. The 5-years survival rate of partial and total group were 62.58% and 68.74% respectively. The survival curve of both groups had no significant difference （P〈O. 05）. Conclusion：For laryngeal carcinoma patients at later stage, with suitable operative indication, the partial laryngectomy could achieve an acceptable effect as well as total laryngeetomy.
出处
《临床耳鼻咽喉头颈外科杂志》
CAS
北大核心
2013年第15期844-846,共3页
Journal of Clinical Otorhinolaryngology Head And Neck Surgery
关键词
喉肿瘤
生存分析
部分喉切除术
全喉切除术
laryngeal cancer
survival analysis
parlial laryngectomy
total laryngectomy
