期刊文献+

新辅助化疗在局部晚期子宫颈癌中的近期临床疗效观察 被引量:6

Observation of recent clinical efficacy of neoadjuvant chemotherapy in treatment of locally advanced cervical cancer
暂未订购
导出
摘要 目的探讨新辅助化疗治疗局部晚期子宫颈癌中的实际效果。方法选取我院2010年11月~2012年7月入院治疗的30例局部晚期子宫颈癌患者为研究对象,针对治疗效果进行了比较研究。结果本研究的全部30例患者总有效(CR+PR)24例,总有效率达80.00%。从肿瘤大小变化情况上看,所有患者治疗后肿瘤均明显缩小,差异均具有统计学意义(P均<0.05)。结论针对局部晚期子宫颈癌患者实施相关的新辅助化疗,其临床实际效果显著安全有效。 Objective To investigate the recent clinical efficacy of neoadjuvant chemotherapy in treatment of locally advanced cervical cancer. Methods 30 patients with locally advanced cervical cancer treated in our hospital from November 2010 to July 2012 were selected. The treatment effect were compared and discussed. Results The total effective(CR+PR) was 24 cases in all 30 cases of the present study, the total effective rate was 80%. From the tumor size changes of point of view, the tumors of all patients were significantly reduced after treatment, and the differences were statistioally significant(P 〈 0.05). Conclusion The clinical effect of neoadjuvant chemotherapy for patients with locally advar^ed cervical cancer was safe and effective.
出处 《中国医药科学》 2013年第15期195-196,共2页 China Medicine And Pharmacy
关键词 新辅助化疗 局部晚期子宫颈癌 近期临床疗效 Neoadjuvant chemotherapy Locally advanced cervical cancer Recent clinical efficacy
  • 相关文献

参考文献7

二级参考文献46

  • 1邵四海,王荣江,石麒麟,赵红星,郑银元,李辉,陈晓农.动脉化疗栓塞对膀胱癌组织中增殖细胞核抗原表达的影响[J].中国全科医学,2009,12(9):732-733. 被引量:2
  • 2杨琳,谢榕,林玉珍.宫颈癌术前新辅助化疗的临床应用[J].中国肿瘤,2009,18(12):1021-1022. 被引量:2
  • 3许彩芹,崔金全.紫杉醇在宫颈癌新辅助化疗中的应用[J].国外医学(妇幼保健分册),2005,16(6):413-415. 被引量:25
  • 4卞美璐.WHO(2006年)宫颈癌综合防治实践指南简介[J].中国实用妇科与产科杂志,2007,23(7):557-560. 被引量:106
  • 5Benedetti Panici P,Bellati F,Pastore M,et al. An update in neoadjuvant chemotherapy in cervical cancer. Gynecol Oncol, 2007,107( 1 Suppl 1 ) :S20-22.
  • 6Rein DT, Kurbacher CM, Breidenbach M ,et al. Weekly carboplatin and docetaxel for locally advanced primary and recurrent cervical cancer:, a phase I study. Gyneeol Oneol, 2002,87( 1 ) : 98-103.
  • 7Ki KD, Song DH, Tong SY, et al. Neoadjuvant chemotherapy in bulky stage IB-IIA cervical cancer: results of a quick course with vincristine, bleomycin, and cisplatin [J]. Int J Gynecal Cancer,2009,19(1):50-53.
  • 8Hirabayashi K, Ito J, Kobayashi M, et al. Taxol in advanced cervical cancer [J]. Nippon Rinsho,2004,62(Suppl 10):179-182.
  • 9Nakazawa G, Finn AV, Vorpahl M, et al. Coronary responses and differential mechanisms of late stent thrombosis attributed to first- generation sirolimus- and paclitaxel-eluting stents [J]. J Am Coil Cardiol,2011,57(4):390-398.
  • 10Takeyoshi I, Makita F, Tanahashi Y, et al. A phase Ⅱ study of weekly paclitaxel and doxifluridine combination chemotherapy for advanced/ recurrent gastric cancer [J]. Anticancer Res,2011,31(1):287-291.

共引文献27

同被引文献43

  • 1Loizzi V, Cormio G, Vicino M, et al. Neoadjuvant chemotherapy : an alternative option of treatment for locally advanced cervical cancer[ J]. Gynecol Obstet Invest, 2008,65 (2) :96-103.
  • 2Bae JW, Lee JH, Choi JS, et al. Laparoscopic lymphadenectomy for gynecologic malignancies: evaluation of the surgical approach and out- comes over a seven -year experience[J]. Arch Gynecol Obstet, 2012, 285(3) :823 -829.
  • 3Dechemey AH, Nathan L, Huang A. Current Obstetric and Gynecologic Diagnosis and Treatment [ M ]. McGraw-Hill Education ( Asia ) Co, 2004:722 - 729.
  • 4王晓萍.新辅助化疗治疗Ib2~IIb期子宫颈癌的疗效评价[J].甘肃:兰州大学,2010.
  • 5Duefias - Gonzalez A, Cetina L, Mariscal I, et al. Modem management of locally advanced cervical carcinoma[ J]. Cancer Treat Rev, 2003,29 (5) :389 -399.
  • 6Moore DH. Treatment of stage IB2 (bulky) cervical carcinoma [ J ]. Cancer Treat Rev, 2003,29 ( 5 ) : 401 - 406.
  • 7Vandecasteele K, Makar A, Van den Broecke R, et al. In- tensity- modulated arc therapy with cisplatin as neo - adju- vant treatment for primary irresectablecervical cancer. Toxic- ity, tumour response and outcome[ J ]. Strahlenther Onkol,2012, 188(7): 576.
  • 8Islam S, Mukhopadhyay L, Howells R. Neo- adjuvant chemotherapy and radical surgery for stage 1B cervical cancer in pregnancy[J]. J Obstet Gynaecol, 2012, 32(2) : 191.
  • 9Zanaboni F, Grijuela B, Giudici S, et al. Weekly topotecan and cisplatin (TOPOCIS) as neo - adjuvant chemotherapy for locally- advanced squamous cervical carcinoma: Results of a phase Ⅱ multicentric study[J]. Eur J Cancer, 2013, 49(5): 1065.
  • 10Fanfani F, Fagotti A, Gagliardi M L, et al. Pre- hysterec- tomy cone biopsy is able to predict response in locally ad- vanced cervical cancer patients submitted to neo - adjuvant cbemoradiation[J]. Eur J Surg Oncol, 2013, 39(9) : 1025.

引证文献6

二级引证文献34

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部