摘要
目的评价血液透析(HD)联合血液透析滤过(HDF)模式对促红细胞生成素(EPO)治疗终末期肾病(ESRD)经济困窘患者肾性贫血的影响。方法选择2010年4月～2011年12月我院HD联合HDF模式治疗肾性贫血患者40例,维持性血液透析(MHD)肾性贫血患者20例,两组均予EPO静脉注射,于用药前及用药后每4周检测Hb、HCT、RBC等指标,同时观察临床症状改善情况。结果治疗4个月后HD联合HDF模式组Hb、HCT、RBC比用药前显著升高,与MHD组比较差异有统计学意义。结论 HD联合HDF模式可提高EPO治疗ESRD肾性贫血效果,优于MHD。
Objective To explore the effect of combination of hemodialysis（HD） and hemodiafiltration（HDF） in the treatment of renal anemia by recombinant human erythropoietin（EPO） in the end-stage renal disease（ESRD） patients with shortage of medical expenses.Methods Forty patients with renal anemia in the Rich Hospital kidney center were selected from April 2010 to December 2011,using the combination of HD and HDF;the control group was 20 maintenance hemodialysis（MHD） patients with renal anemia from the same center.Both groups were treated with EPO weekly twice after hemodialysis by intravenous injection.The changes of Hb,HCT and RBC were detected every 4 weeks,including the observation of clinical symptoms.Results The levels of Hb,HCT and RBC were significantly increased in HD combined with HDF group patients who accepted EPO treatment for 4 months than that of control group（P0.05）,no adverse reactions were detectable.Conclusion The combination of HD and HDF for EPO treatment of ESRD patients with renal anemia who had shortage of medical expenses shows significantly better than MHD.
出处
《四川医学》
CAS
2013年第6期860-861,共2页
Sichuan Medical Journal
基金
南通市社会发展基金(编号:HS2011053)
