摘要
目的:对小儿热性惊厥复发的临床高危因素进行研究,为临床预防热性惊厥复发的发生提供可能的支持。方法:随机选取2002～2010年苏州大学附属儿童医院确诊为上呼吸道感染及热性惊厥复发患儿30例作为观察组,有上呼吸道感染及高热但未发生热性惊厥的患儿30例分为对照组,两组年龄及性别无统计学差异。观察两组患儿16个指标(如:性别、年龄、日托儿童等),再将阳性结果放入Logistic回归方程进行多因素分析。结果:发现观察组患儿中:日托儿童,一、二级亲属中热性惊厥史、围产期异常史、发育迟缓史、代谢性酸中毒、低血钠、低血锌、低钙、低血镁、缺铁性贫血、脑电图异常、头颅CT异常与对照组比较有统计学差异(P<0.05)。再将上述高危因素放入Logistic回归方程进行多因素分析,发现日托儿童,一、二级亲属中热性惊厥史、围产期异常史、低血钠、低血锌、缺铁性贫血与热性惊厥复发的发生有显著相关性。结论:日托儿童、家族史、围产期异常史、低血钠、低血锌,缺铁性贫血与热性惊厥复发有显著相关性,以上结论可进一步指导临床,预防热性惊厥复发的发生。
Objective： To study the clinical risk factors of recurrence of febrile seizures in children for clinical prevention of recur-rence of febrile seizures in the occurrence of febrile may provide support. Methods： From 2002 to 2010, 30 patients with upper respiratory tract infection and febrile seizure were randomly selected and divided into observation group and 30 cases with upper respiratory tract infection and fever but without febrile seizure were divided into control group. There were no significant differences in age and sex between two groups. 16 indicators such as： gender, age, day care children and so on were observed. The positive results were put into Logistic regression equa- tion for the analysis of multiple factors. Results： There were significant differences in day care children, one or two family history of febrile seizure, perinatal abnormalities history, growth retardation, metabolic acidosis, low sodium, low blood zinc, low calcium, low blood magne-sium, iron deficiency anemia, EEG abnormalities, abnormal cranial CT between two groups （ P 〈 0. 05 ）. Day care children, one or two fam-ily history of febrile seizure, perinatal abnormalities history, low sodium, low blood zinc, iron deficiency anemia were all independent risk factors of recurrence of febrile seizures in pediatric. There were significant correlations between day care children, family history, histories of perinatal abnormalities, low sodium, low blood zinc, iron deficiency anemia and the recurrence of febrile seizures. Conclusion： There are significant correlations between day care children, family history, histories of perinatal abnormalities, low sodium, low blood zinc, iron defi- ciency anemia and the recurrence of febrile seizures, which provides important help for diagnosis and treatment, prevention of the occurrence of febrile seizures recurrence.
出处
《中国妇幼保健》
CAS
北大核心
2013年第23期3779-3781,共3页
Maternal and Child Health Care of China
关键词
热性惊厥
高危因素
回归分析
Febrile seizures
Risk factors
Logistic regression analysis
