摘要
目的检测外周血血小板参数的变化在急性脑梗死(CI)患者诊疗中应用价值。方法应用全自动血细胞分析仪,对82例急性脑梗死患者及50例健康体检者(对照组)进行血小板参数[主要指血小板计数(PLT)、未成熟血小板比率(IPF)、血小板平均体积(MPV)、血小板分布宽度(PDW)]的检测,82例患者按不同发病时间段分为1～7d及8～14d两个检测组各41例,分别与对照组进行血小板参数的比较。结果 CI发病1～7d组与健康对照组比较,IPF值两组比较差异有显著统计学意义(P<0.01),PLT、MPV、PDW两组对比差异有统计学意义(P<0.05);CI发病8～14d组与健康对照组比较,PDW两组比较差异有统计学意义(P<0.05),PLT、MPV、IPF两组比较差异无统计学意义(P>0.05)。结论监测急性脑梗死患者外周血血小板参数不同时间段的变化,有助于临床观察脑梗死患者病情的疗效及预防、预后的判断。
Objective To detect the changes ofplatelet parameters in the peripheral blood and its application value in the diagnosis of acute cerebral infarction. Methods Automatic blood cell analyzer was used to detect platelet parameters （the platelet count, the immature platelet ratio, mean platelet volume, platelet distribution width） in 82 cases of acute cerebral infarction and 50 normal cases. They were divided into 1 to 7 days group and 8 to 14 days group according to different onset period, and platelet parameters were compared with the control group. Results Compared between CI 1 - 7 d group and control group, the difference of IPF was statistically significant （P〈0.01）, and the differences of PLT, MPV, PDW was statistically significant （P 〈0.05）. Compared between CI 8 -14 group and control group, the difference of PDW was statistically significant （P〈0.05）, but the differences of PLT, MPV, IPF were not statistically significant （P〉0.05）. Conclusions Monitoring of the changes ofplatelet parameters in patients with acute cerebral infarction at different time period is helpful to the clinical efficacy and prevention, prognosis of patients with cerebral infarction disease.
出处
《临床医学工程》
2013年第8期967-968,共2页
Clinical Medicine & Engineering
