摘要
罗马Ⅲ标准将功能性消化不良(FD)分为上腹痛综合征、餐后不适综合征以及混合型三种,学者们对此存在争议。从FD不同症状及其生理病理关系上寻找更科学的分型,方能采取更有针对性的治疗。FD发病机制尚不完全明确,可能与感染、胃肠运动功能障碍、内脏高敏感性、基因易感性、脑肠轴功能失调以及心理社会因素等有关。西医采用根除幽门螺旋杆菌、促进胃动力、抑酸等治疗,中医药从整体出发,多层次、多靶点、多途径对胃肠运动、胃肠激素等进行调节,近年来取得了一定进展。中医药对FD病因病机、流行病学、临床诊疗等方面研究都取得可喜成绩,从整体出发,单味药、成方复方、针灸可多层次、多靶点、多途径地对胃肠运动、胃肠激素等进行调节。未来期待进一步强化随机、对照、双盲实验及基础研究,临床观察注重远期随访。
Functional dyspepsia（FD）,the upper abdominal pain syndrome,postprandial distress syndrome,and three mixed,and this typing method,there are some controversial,to find from the different symptoms of FD patients and their physiological and pathological relationsmore scientific type,or take a more targeted treatments.FD pathogenesis is not entirely clear,its pathogenesis may be associated with infection,dysfunction of the gastrointestinal motility,visceral hypersensitivity,genetic predisposition,brain-gut axis dysfunction,and psychosocial factors.Western medicine treatment can be used to eradicate Helicobacter pylori promote gastric motility,acid suppression therapy,Chinese medicine is a holistic approach,can be multi level,multi-target,multi-channel to be adjusted on gastrointestinal motility,gastrointestinal hormones,has been made in recent years some progress.
出处
《实用中医内科杂志》
2013年第4期150-152,共3页
Journal of Practical Traditional Chinese Internal Medicine
关键词
功能性消化不良
发病机制
研究进展
中西医治疗
综述
Functional dyspepsia
Pathogenesis
Advance research
Treatment of traditional Chinese and Western medicine
