摘要
目的探讨短暂性脑缺血发作(TIA)患者颅内外血管狭窄与临床发作之间的相关性。方法选择112例行全脑血管造影的TIA患者,分析颅内外动脉狭窄的发生率、分布、程度及斑块情况,探讨发作频率、发作持续时间与血管狭窄程度的相关性。结果 78例存在颅内外血管狭窄,占69.6%(78/112),其中颅内血管狭窄占61.5%(48/78),颅外血管狭窄占38.5%(30/78)。狭窄部位有斑块66例,占狭窄血管84.6%(66/78)。狭窄程度≥70%者占39.3%(44/112),50%～70%者占7.1%(8/112),<50%者占23.2%(26/112)。频发组血管总狭窄率、中重度狭窄率均高于非频发组(P均<0.05)。中重度血管狭窄患者发作持续时间<10min者高于轻度血管狭窄患者(P<0.05)。结论 TIA患者颅内外血管狭窄多,多伴有粥样硬化性斑块,是TIA的主要病因。狭窄发生部位以颅内动脉多见。发作频率、发作持续时间均与血管狭窄呈一定的相关性。
Objective To investigate the relationship between intracranial and extracrania[ artery stenosis and clinical attack characteristics in patients with transient ischemic attack （TIA）. Method 112 TIA patients received digital substract angiography were admitted. The frequency, distribution, degree, and plaque of intracranial and extracranial artery stenosis were analysed, and the relations between frequency and duration of transient ischemic attack and stenosis degree were studied. Results 69. 6% （78/112） of the patients were found with intracranialand extracranial artery stenosis, 61.5% （48/78） of which involved in intracranial artery and the rest in extracranial artery. 84.6% （66/78） of stenosis had plaque. Among all patients, those with stenosis degree ≥70 % accounted for 39.3% （44/112）, with ste nosis degree about 50% to 70% accounted for 7.1% （8/112）, and with stenosis degree 〈50% accounted for 23.2%（26/112）. Total stenosis degree and the degree of moderate-severe stenosis in the frequently attack subgroup were higher than those in the non-frequently-attack subgroup （P〈0.05）. Patients with moderate-severe stenosis who suffered shorter than 10 min of TIA were more than those with mild stenosis （P〈0.05）. Conclusion Intracranial and extracranial artery stenosis and stenosis with plague are the main reasons for TIA. The frequency and duration of TIA have correlation with artery stenosis.
出处
《福建医科大学学报》
2013年第2期110-112,共3页
Journal of Fujian Medical University
关键词
脑动脉
脑梗死
脑缺血发作
短暂性
动脉粥样硬化
动脉闭塞性疾病
cerebral arteries
brain infarction
ischemic attack, transient
atherosclerosis
arterial occlusive diseases
