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手术前后肠内营养支持用于合并营养风险胃癌患者的临床观察

Application of preoperative and postoperative enteral nutrition in the gastric cancer patients with nutritional risk
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摘要 目的 探讨手术前后肠内营养支持对合并营养风险胃癌患者营养状况的影响.方法 将有营养风险的72例胃癌患者采用随机数字表法分为两组,肠外营养组(PN组)36例,行术后常规静脉营养支持;肠内营养组(EN组)36例,从术前第5天到术后第8天给予肠内营养支持.两组均于术前第5天、术晨、术后第1天和术后第8天测量体质量,测定血清总蛋白、白蛋白、转铁蛋白和前白蛋白.结果 EN组术晨转铁蛋白和前白蛋白水平高于PN组(P<0.05);术后第8天,EN组体质量、总蛋白、白蛋白、转铁蛋白和前白蛋白均高于PN组(均P<0.05);EN组术晨转铁蛋白和前白蛋白均较术前第5天升高,差异均有统计学意义(P<0.01).结论 手术前后肠内营养支持可以改善合并营养风险胃癌患者的营养状况.而术前进食肠内营养,可以提高胃癌患者术前营养状况,改善术前的营养储备,降低术后肠内营养的不良反应. Objective To investigate the significance of preoperative and postoperative enteral nutrition sup- port in gastric cancer patients with nutritional risk. Methods The clinical data of 72 gastric cancer patients with nu- tritional risk admitted in our department .were analyzed. All the patients were randomly allocated into two groups. 36 patients in the control group received only intravenous nutrition postoperatively (PN group).36 patients in the treat- ment group received enteral nutrition support from the fifth day before operation to eighth day after operation ( EN group). The body weight, total protein, albumin, transferrin and prealbumin were measured on the fifth day before op- eration, the operation morning, the first day and the eighth day after operation. Results On the operation morning, the transferrin and prealbumin of the EN group were higher than those in PN group significantly(P 〈 0.05). In the eighth day after operation, the treatment group patients showed significant increase in the body weight, total protein, albumin, transferrin and prealbumin compared with those in the control group ( P 〈 0.05 ). On the operation morning, the trans- ferrin and prealbumin of EN group were increased significantly than on the fifth day before operation ( P 〈 0. O1 ). Conclusion The preoperative and postoperative enteral nutritional support can improve the nutritional condition in the gastric cancer patients with nutritional risk. The preoperative enteral nutritional support can improve the patients" nutritional condition and reserves before operation, and reduce adverse reaction of enteral nutrition.
出处 《中国基层医药》 CAS 2013年第15期2322-2323,共2页 Chinese Journal of Primary Medicine and Pharmacy
关键词 胃肿瘤 术前术后肠内营养 营养风险 Gastric neoplasms Preoperative and postoperative enteral nutrition Nutritional risk
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