摘要
目的探讨针吸细胞学涂片对非霍奇金淋巴瘤研究的临床价值。方法复查2008年12月-2012年12月,来蚌埠医学院第一附属医院进行针吸细胞学检查的门诊及住院患者的针吸涂片,根据非霍奇金淋巴瘤细胞学特点,并与组织病理对照,对诊断结果进行分析。结果共查出非霍奇金淋巴瘤126例,其中滤泡中心淋巴瘤42例,占33.3%(42/126)。套细胞淋巴瘤40例,占31.8%(40/126)。弥漫性大B细胞淋巴瘤21例,占16.7%(21/126)。浆母细胞性淋巴瘤11例,占8.7%(11/126)。间变性大细胞淋巴瘤7例,占5.6%(7/126)。曲核细胞淋巴瘤5例,占4.0%(5/126)。结论通过对非霍奇金型淋巴瘤细胞,进行反复对比和形态特征等分析,发现各型非霍奇金淋巴瘤细胞是由B细胞和T细胞通过不同转化途径而形成,且具有各自细胞特征及相互演变的过度形。加深了对各型非霍奇金淋巴瘤细胞的识别能力,有助于临床诊断治疗,及预后观察。
Objective To investigate clinical value of fine needle aspiration smears on studying of non-Hodgkin’S lymphoma(NHL).Methods Fine needle aspiration smears of outpatients and inpatients of our hospital from December,2008 to December,2012 were reexamined.The results were analyzed by observing cytological characteristics of NHL and comparing with histopathology.Results All 126 cases of NHL including 42(33.3%) cases of Follicular lymphoma,40(31.8%) cases of mantle cell lymphoma,21(16.7%) cases of diffuse large B-cell lymphoma,11(8.7%) cases of plasmablast type lymphoma,7(5.6%) cases of anaplastic large cell lymphoma and 5(4.0%) cases of convoluted cell lymphoma were found.Conclusion After proceeding repeat comparison and morphological characteristics analysis of NHL cells,we found that each type of NHL cells was formed by B cells or T cells through different transformation way,and had its own cell characteristics and mutual evolution excessive shapes.These discoveries could help us improve our ability of identifying NHL cells,and help clinical staff to diagnose and cure NHL and judge its prognosis.
出处
《中华全科医学》
2013年第8期1284-1285,共2页
Chinese Journal of General Practice
关键词
淋巴瘤
非霍奇金淋巴瘤
针吸涂片
Lymphoma
Non-hodgkin’s lymphoma
Fine needle aspiration smear