摘要
目的评价两种同种异体骨修复材料在脊柱融合手术中使用后的融合效果及有效性、安全性。方法 2007年5月至2008年6月,对江苏省人民医院骨科收治的33例胸腰椎骨折患者和11例脊柱退变疾病患者,采用两种同种异体骨修复材料进行脊柱融合手术。观察两组患者手术前后生化指标及局部情况判断安全性同时比较融合率。结果术后随访24周,试验组未发生不良反应,对照组发生2例不良反应,两组不良反应发生率比较无明显差异,术后红肿、积液、渗出量等局部症状两组无明显差异。术后融合率无明显差异。结论北京德得创业科技有限公司研制的同种异体骨修复材料具有良好的安全性与有效性,在脊柱融合手术中应用,能取得满意的临床效果。
Objective To assess the clinical efficacy and safety of two kinds of allograft bone after surgery of spinal fusion.Methods From May,2007 to June,2008,totally 44 patients with spinal fractures（33 patients） and spinal degeneration diseases（11 patients） were taken allograft bone implantation in spinal fusion.Their clinical data were collected to analyze biochemical indicator before and after operation,healing of postoperative incision.After operation,foreign body reaction was studied clinically and spinal fusion status was assessed radiographically.Results No significant foreign body reaction or chronic deep wound infection occurred in all patients.There was no significant difference in fusion rate between two groups.Conclusions The allograft bone by DoDone technology company is of good tissue compatibility and able to promote bone formation.A satisfactory outcome can be achieved in posterior spinal fusion.
出处
《齐齐哈尔医学院学报》
2013年第13期1889-1890,共2页
Journal of Qiqihar Medical University
关键词
脊柱融合术
同种异体骨
骨移植
Spinal fusion
Allograft bone
Bone transplantation
