摘要
目的探讨2型糖尿病患者发生糖尿病足溃疡的相关因素。方法对1年内北京潞河医院所有住院的糖尿病足溃疡患者资料进行收集,包括常规生化检查、器官功能检查,根据病情进行Wagner分级,比较糖尿病足溃疡患者与对照组(同期入院的非糖尿病足溃疡的2型糖尿病患者)的各项临床指标,评估这些指标对糖尿病足溃疡发生的风险差异。结果糖尿病足溃疡患者的心功能、肾功能、血浆白蛋白、血红蛋白等与对照组比较,差异有统计学意义(P<0.05);糖尿病足溃疡患者组年龄较对照组大,差异有统计学意义(P<0.01)。用逐步多元回归分析DFU独立危险因素,发现糖尿病病程是DFU的独立危险因素(r=0.911 6,P<0.05);提示患者存在大血管病变的指标中,冠心病、脑血管病、心功能分级为DFU的独立危险因素(r=2.118 7、r=2.074 8、r=1.182 0,P<0.05);尿微量白蛋白也是DFU的独立危险因素(r=1.1962,P<0.05)。结论糖尿病足溃疡的预防重在延缓大血管和微血管的并发症,发现异常及时治疗。糖尿病患者一旦发生糖尿病足溃疡,即伴随诸多器官功能障碍,特别是心肾功能差,因此治疗中需要加强全身状态的监控及干预。
Objective To investigate the relevant factors for type 2 diabetes patients with diabetic foot ulcers.Methods Data of all hospitalized patients with diabetic foot ulcers in Beijing Luhe Hospital the past year was collected,including routine biochemical tests,organ function tests.Grading patients with the Wagner classification according to the different status.Control group was consist of type 2 diabetes patients without diabetic foot ulcers the same time in Beijing Luhe Hospital.comparison of diabetic foot ulcer patients and the control group with clinical indicators to assess these indicators of diabetic foot ulcer risk.Results Cardiac function,renal function,serum albumin and hemoglobin of type 2 diabetic patients with diabetic foot ulcers were worse than control group（P＆lt;0.05）.The age of patients with diabetic foot ulcers group was significantly elder（P＆lt;0.05）.Stepwise multiple regression analysis of DFU independent risk factors indicated that the duration of diabetes was the the DFU independent risk factors（r=0.911 6,P＆lt;0.05）,and indicated that patients with macrovascular disease,coronary heart disease,cerebrovascular disease,heart function classified as the DFU independent risk factors（r=2.118 7,r=2.074 8,r=1.182 0,P＆lt;0.05）,and that urinary albumin was an independent risk factor DFU（r=1.196 2,P＆lt;0.05）.Conclusion Delaying macrovascular and microvascular complications is most important in preventing diabetic foot ulcers,and so is early treatment.Diabetic patients with diabetic foot ulcers show that patients may have had a lot of organ dysfunction,especially heart and kidney function.Treatments of diabetes need to be strengthened on control and intervention of systemic state.
出处
《湖南中医药大学学报》
CAS
2013年第6期22-23,共2页
Journal of Hunan University of Chinese Medicine
关键词
糖尿病足溃疡
大血管病变
微血管病变
Diabetic foot ulcers
Macroangiopathy
Microvascular disease
