摘要
目的探讨静吸复合麻醉对颅内手术患者麻醉用量及不良反应的影响。方法选取我院2012年1月至2012年12月采取静吸复合麻醉方式行颅内手术患者60例,随机分成A、B、C三组,分别给予患者不同麻醉用量,观察不同麻醉用量麻醉效果和不良反应情况。结果 A组不良反应3例,发生率为15.0%,B组9例(30.0%),C组21例(70.0%);A组和B组麻醉效果差异明显(P<0.05),B组和C组麻醉效果比较无显著差异(P>0.05)。结论对于采取静吸复合麻醉方式行颅内手术患者,2～3μg/mL血浆靶浓度丙泊酚复合4～6ng/mL血浆靶浓度瑞芬太尼与3～5μg/ml丙泊酚复合6～8ng/mL血浆靶浓度瑞芬太尼麻醉效果与无明显差异,不良反应较少,值得进一步研究和临床推广应用。
Objective To study the static absorption dosage of compound anesthesia in patients with intracranial surgery anesthesia and the impact of adverse reactions. Methods From January 2012- December 2012 static absorption compound anesthesia ways line of 60 patients with intracranial surgery, were randomly divided into A, B, C three groups and were given different dosage of anesthetic patients, observe the different dosage of anesthetic effects and adverse reactions. Results Incidence of adverse reactions for group A, group B 9 cases （30.0%）, 21 cases of group C （70.0%）; Clear difference anesthetic effect in group A and group B （P〈0.05）, group B and group C anesthesia effect is no significant difference （P〉0.05）. Conclusion To adopt static absorption line compound anesthesia of intracranial surgery patients, 2-3 μg/mL plasma concentration of propofol target compound 4, 6 ng/mL target plasma concentration, fentanyl and 3-5μg/mL propofol compound 6-8 ng/mL, fentanyl anesthesia target plasma concentration effect and no obvious difference, with less adverse reactions, worthy of further research and clinical application.
出处
《中国医药指南》
2013年第16期493-494,共2页
Guide of China Medicine
关键词
静吸复合麻醉
颅内手术患者
麻醉用量
不良反应
Inhalation anesthesia
Intracranial surgery
Anesthetic dosage
Adverse reactions
